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Imaging in gynecological disease (7): clinical and ultrasound features of Brenner tumors of the ovary

Dierickx, I.; Valentin, Lil LU ; Van Holsbeke, C.; Jacomen, G.; Lissoni, A. A.; Licameli, A.; Testa, A.; Bourne, T. and Timmerman, D. (2012) In Ultrasound in Obstetrics & Gynecology 40(6). p.706-713
Abstract
Objectives To describe clinical and ultrasound features of Brenner tumors of the ovary. Methods In this retrospective study, the databases of the International Ovarian Tumor Analysis (IOTA) studies and one tertiary center were searched to identify patients who had undergone an ultrasound scan before surgery for an adnexal mass that proved to be a Brenner tumor. Twenty-eight patients with 29 Brenner tumors were included, most of which had been collected within the framework of the IOTA studies. An experienced ultrasound examiner reviewed available ultrasound images (available for 14 tumors), searching for a pattern specific to Brenner tumors. Results Most patients were postmenopausal and asymptomatic. Twenty-four (83%) tumors were benign,... (More)
Objectives To describe clinical and ultrasound features of Brenner tumors of the ovary. Methods In this retrospective study, the databases of the International Ovarian Tumor Analysis (IOTA) studies and one tertiary center were searched to identify patients who had undergone an ultrasound scan before surgery for an adnexal mass that proved to be a Brenner tumor. Twenty-eight patients with 29 Brenner tumors were included, most of which had been collected within the framework of the IOTA studies. An experienced ultrasound examiner reviewed available ultrasound images (available for 14 tumors), searching for a pattern specific to Brenner tumors. Results Most patients were postmenopausal and asymptomatic. Twenty-four (83%) tumors were benign, two (7%) were borderline and three (10%) were malignant. Most benign tumors (17/24, 71%) contained solid components and manifested no or minimal blood flow on Doppler examination (19/24, 79%). Information about calcifications was available for 15 benign tumors, and in 13 (87%) calcifications were present. The five borderline and invasively malignant tumors contained solid components less often than did the benign ones (3/5, 60%) and were more richly vascularized on Doppler examination. Information about calcifications was available for four borderline or invasively malignant tumors, and in three (75%) calcifications were present. Conclusion We failed to demonstrate ultrasound features specific to Brenner tumors. A prospective study is needed to determine if ultrasound features of calcifications can discriminate between Brenner tumors and other types of ovarian tumor. Copyright (c) 2012 ISUOG. Published by John Wiley & Sons, Ltd. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Brenner tumor, ovarian neoplasms, preoperative diagnosis, ultrasonography
in
Ultrasound in Obstetrics & Gynecology
volume
40
issue
6
pages
706 - 713
publisher
John Wiley & Sons
external identifiers
  • wos:000311857700017
  • scopus:84870542537
ISSN
1469-0705
DOI
10.1002/uog.11149
language
English
LU publication?
yes
id
ae90bc27-2f45-4071-85f9-aadf5c42978a (old id 3372778)
date added to LUP
2013-02-01 07:00:58
date last changed
2017-08-13 03:58:11
@article{ae90bc27-2f45-4071-85f9-aadf5c42978a,
  abstract     = {Objectives To describe clinical and ultrasound features of Brenner tumors of the ovary. Methods In this retrospective study, the databases of the International Ovarian Tumor Analysis (IOTA) studies and one tertiary center were searched to identify patients who had undergone an ultrasound scan before surgery for an adnexal mass that proved to be a Brenner tumor. Twenty-eight patients with 29 Brenner tumors were included, most of which had been collected within the framework of the IOTA studies. An experienced ultrasound examiner reviewed available ultrasound images (available for 14 tumors), searching for a pattern specific to Brenner tumors. Results Most patients were postmenopausal and asymptomatic. Twenty-four (83%) tumors were benign, two (7%) were borderline and three (10%) were malignant. Most benign tumors (17/24, 71%) contained solid components and manifested no or minimal blood flow on Doppler examination (19/24, 79%). Information about calcifications was available for 15 benign tumors, and in 13 (87%) calcifications were present. The five borderline and invasively malignant tumors contained solid components less often than did the benign ones (3/5, 60%) and were more richly vascularized on Doppler examination. Information about calcifications was available for four borderline or invasively malignant tumors, and in three (75%) calcifications were present. Conclusion We failed to demonstrate ultrasound features specific to Brenner tumors. A prospective study is needed to determine if ultrasound features of calcifications can discriminate between Brenner tumors and other types of ovarian tumor. Copyright (c) 2012 ISUOG. Published by John Wiley & Sons, Ltd.},
  author       = {Dierickx, I. and Valentin, Lil and Van Holsbeke, C. and Jacomen, G. and Lissoni, A. A. and Licameli, A. and Testa, A. and Bourne, T. and Timmerman, D.},
  issn         = {1469-0705},
  keyword      = {Brenner tumor,ovarian neoplasms,preoperative diagnosis,ultrasonography},
  language     = {eng},
  number       = {6},
  pages        = {706--713},
  publisher    = {John Wiley & Sons},
  series       = {Ultrasound in Obstetrics & Gynecology},
  title        = {Imaging in gynecological disease (7): clinical and ultrasound features of Brenner tumors of the ovary},
  url          = {http://dx.doi.org/10.1002/uog.11149},
  volume       = {40},
  year         = {2012},
}