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Neutrophilic and Eosinophilic Dermatitis Caused by Contact Allergic Reaction to Paraphenylenediamine in Hair Dye

Lonngren, Vincent; Young, Ewa LU ; Simanaitis, Mecius and Svedman, Cecilia LU (2012) In Archives of Dermatology 148(11). p.1299-1301
Abstract
Background: Paraphenylenediamine (PPD) in hair dyes can cause systemic as well as cutaneous allergic reactions such as neutrophilic and eosinophilic dermatitis. The symptoms are often severe. The acute lesion is normally histologically indistinguishable from any eczematous reaction with marked spongiosis. Observations: We report a case of allergic contact dermatitis caused by the use of hair dye containing PPD that developed in a patient who had been using the same hair dye for many years. Her symptoms included scalp dermatitis and widespread skin lesions as well as lymphadenopathy and quite possibly dyspnea resembling asthma. What is most remarkable about this case is the histopathologic finding of neutrophilic cellulitis and a marked... (More)
Background: Paraphenylenediamine (PPD) in hair dyes can cause systemic as well as cutaneous allergic reactions such as neutrophilic and eosinophilic dermatitis. The symptoms are often severe. The acute lesion is normally histologically indistinguishable from any eczematous reaction with marked spongiosis. Observations: We report a case of allergic contact dermatitis caused by the use of hair dye containing PPD that developed in a patient who had been using the same hair dye for many years. Her symptoms included scalp dermatitis and widespread skin lesions as well as lymphadenopathy and quite possibly dyspnea resembling asthma. What is most remarkable about this case is the histopathologic finding of neutrophilic cellulitis and a marked neutrophilic infiltrate with variable spongiosis. This unique finding was confirmed by histologic analysis of a patch test lesion specimen. Conclusion: It is always important to consider contact allergic dermatitis as a cause of dermatitis because of the variable presentation of the disease, including unique histologic findings that do not fit the conventional picture, as in the present case. Arch Dermatol. 2012;148(11):1299-1301 (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Archives of Dermatology
volume
148
issue
11
pages
1299 - 1301
publisher
American Medical Association
external identifiers
  • wos:000311365700014
  • scopus:84869843513
ISSN
0003-987X
DOI
10.1001/archdermatol.2012.2586
language
English
LU publication?
yes
id
1cfc84f6-f9de-4d84-93f6-eb99fc63b97e (old id 3373232)
date added to LUP
2013-02-01 07:01:28
date last changed
2017-05-21 03:54:37
@article{1cfc84f6-f9de-4d84-93f6-eb99fc63b97e,
  abstract     = {Background: Paraphenylenediamine (PPD) in hair dyes can cause systemic as well as cutaneous allergic reactions such as neutrophilic and eosinophilic dermatitis. The symptoms are often severe. The acute lesion is normally histologically indistinguishable from any eczematous reaction with marked spongiosis. Observations: We report a case of allergic contact dermatitis caused by the use of hair dye containing PPD that developed in a patient who had been using the same hair dye for many years. Her symptoms included scalp dermatitis and widespread skin lesions as well as lymphadenopathy and quite possibly dyspnea resembling asthma. What is most remarkable about this case is the histopathologic finding of neutrophilic cellulitis and a marked neutrophilic infiltrate with variable spongiosis. This unique finding was confirmed by histologic analysis of a patch test lesion specimen. Conclusion: It is always important to consider contact allergic dermatitis as a cause of dermatitis because of the variable presentation of the disease, including unique histologic findings that do not fit the conventional picture, as in the present case. Arch Dermatol. 2012;148(11):1299-1301},
  author       = {Lonngren, Vincent and Young, Ewa and Simanaitis, Mecius and Svedman, Cecilia},
  issn         = {0003-987X},
  language     = {eng},
  number       = {11},
  pages        = {1299--1301},
  publisher    = {American Medical Association},
  series       = {Archives of Dermatology},
  title        = {Neutrophilic and Eosinophilic Dermatitis Caused by Contact Allergic Reaction to Paraphenylenediamine in Hair Dye},
  url          = {http://dx.doi.org/10.1001/archdermatol.2012.2586},
  volume       = {148},
  year         = {2012},
}