Phase-difference and spectroscopic imaging for monitoring of human brain temperature during cooling
(2012) In Magnetic Resonance Imaging 30(10). p.1505-1511- Abstract
- Decrease of the human brain temperature was induced by intranasal cooling. The main purpose of this study was to compare the two magnetic resonance methods for monitoring brain temperature changes during cooling: phase-difference and magnetic resonance spectroscopic imaging (MRSI) with high spatial resolution. Ten healthy volunteers were measured. Selective brain cooling was performed through nasal cavities using saline-cooled balloon catheters. MRSI was based on a radiofrequency spoiled gradient echo sequence. The spectral information was encoded by incrementing the echo time of the subsequent eight image records. Reconstructed voxel size was 1x1x5 mm(3). Relative brain temperature was computed from the positions of water spectral lines.... (More)
- Decrease of the human brain temperature was induced by intranasal cooling. The main purpose of this study was to compare the two magnetic resonance methods for monitoring brain temperature changes during cooling: phase-difference and magnetic resonance spectroscopic imaging (MRSI) with high spatial resolution. Ten healthy volunteers were measured. Selective brain cooling was performed through nasal cavities using saline-cooled balloon catheters. MRSI was based on a radiofrequency spoiled gradient echo sequence. The spectral information was encoded by incrementing the echo time of the subsequent eight image records. Reconstructed voxel size was 1x1x5 mm(3). Relative brain temperature was computed from the positions of water spectral lines. Phase maps were obtained from the first image record of the MRSI sequence. Mild hypothermia was achieved in 15-20 min. Mean brain temperature reduction varied in the interval <-3.0; -0.6>degrees C and <-2.7; -0.7>degrees C as measured by the MRSI and phase-difference methods, respectively. Very good correlation was found in all locations between the temperatures measured by both techniques except in the frontal lobe. Measurements in the transversal slices were more robust to the movement artifacts than those in the sagittal planes. Good agreement was found between the MRSI and phase-difference techniques. (C) 2012 Elsevier Inc. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3379486
- author
- Weis, Jan ; Covaciu, Lucian ; Rubertsson, Sten ; Allers, Mats ; Lunderquist, Anders LU ; Ortiz-Nieto, Francisco and Ahlstrom, Hakan
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- MR thermometry, Healthy volunteers, Brain temperature, Phase mapping, Spectroscopic imaging
- in
- Magnetic Resonance Imaging
- volume
- 30
- issue
- 10
- pages
- 1505 - 1511
- publisher
- Elsevier
- external identifiers
-
- wos:000311261000018
- scopus:84868659129
- pmid:22819582
- ISSN
- 1873-5894
- DOI
- 10.1016/j.mri.2012.06.004
- language
- English
- LU publication?
- yes
- id
- bea7a809-e8b0-490f-a6cd-5f341236085d (old id 3379486)
- date added to LUP
- 2016-04-01 10:29:34
- date last changed
- 2022-01-25 23:48:36
@article{bea7a809-e8b0-490f-a6cd-5f341236085d,
abstract = {{Decrease of the human brain temperature was induced by intranasal cooling. The main purpose of this study was to compare the two magnetic resonance methods for monitoring brain temperature changes during cooling: phase-difference and magnetic resonance spectroscopic imaging (MRSI) with high spatial resolution. Ten healthy volunteers were measured. Selective brain cooling was performed through nasal cavities using saline-cooled balloon catheters. MRSI was based on a radiofrequency spoiled gradient echo sequence. The spectral information was encoded by incrementing the echo time of the subsequent eight image records. Reconstructed voxel size was 1x1x5 mm(3). Relative brain temperature was computed from the positions of water spectral lines. Phase maps were obtained from the first image record of the MRSI sequence. Mild hypothermia was achieved in 15-20 min. Mean brain temperature reduction varied in the interval <-3.0; -0.6>degrees C and <-2.7; -0.7>degrees C as measured by the MRSI and phase-difference methods, respectively. Very good correlation was found in all locations between the temperatures measured by both techniques except in the frontal lobe. Measurements in the transversal slices were more robust to the movement artifacts than those in the sagittal planes. Good agreement was found between the MRSI and phase-difference techniques. (C) 2012 Elsevier Inc. All rights reserved.}},
author = {{Weis, Jan and Covaciu, Lucian and Rubertsson, Sten and Allers, Mats and Lunderquist, Anders and Ortiz-Nieto, Francisco and Ahlstrom, Hakan}},
issn = {{1873-5894}},
keywords = {{MR thermometry; Healthy volunteers; Brain temperature; Phase mapping; Spectroscopic imaging}},
language = {{eng}},
number = {{10}},
pages = {{1505--1511}},
publisher = {{Elsevier}},
series = {{Magnetic Resonance Imaging}},
title = {{Phase-difference and spectroscopic imaging for monitoring of human brain temperature during cooling}},
url = {{http://dx.doi.org/10.1016/j.mri.2012.06.004}},
doi = {{10.1016/j.mri.2012.06.004}},
volume = {{30}},
year = {{2012}},
}