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Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation.

Kaufman, Bella ; Shapira-Frommer, Ronnie ; Schmutzler, Rita K ; Audeh, M William ; Friedlander, Michael ; Balmaña, Judith ; Mitchell, Gillian ; Fried, Georgeta ; Stemmer, Salomon M and Hubert, Ayala , et al. (2015) In Journal of Clinical Oncology 33(3). p.134-244
Abstract
Olaparib is an oral poly (ADP-ribose) polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2) -associated breast and ovarian cancers. We evaluated the efficacy and safety of olaparib in a spectrum of BRCA1/2-associated cancers.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Oncology
volume
33
issue
3
pages
134 - 244
publisher
American Society of Clinical Oncology
external identifiers
  • pmid:25366685
  • wos:000352421400008
  • scopus:84921771510
  • pmid:25366685
ISSN
1527-7755
DOI
10.1200/JCO.2014.56.2728
language
English
LU publication?
yes
id
33800f58-da88-435a-8098-ae1b7e7aa410 (old id 4820289)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25366685?dopt=Abstract
date added to LUP
2016-04-01 10:56:43
date last changed
2022-04-28 02:35:06
@article{33800f58-da88-435a-8098-ae1b7e7aa410,
  abstract     = {{Olaparib is an oral poly (ADP-ribose) polymerase inhibitor with activity in germline BRCA1 and BRCA2 (BRCA1/2) -associated breast and ovarian cancers. We evaluated the efficacy and safety of olaparib in a spectrum of BRCA1/2-associated cancers.}},
  author       = {{Kaufman, Bella and Shapira-Frommer, Ronnie and Schmutzler, Rita K and Audeh, M William and Friedlander, Michael and Balmaña, Judith and Mitchell, Gillian and Fried, Georgeta and Stemmer, Salomon M and Hubert, Ayala and Rosengarten, Ora and Steiner, Mariana and Loman, Niklas and Bowen, Karin and Fielding, Anitra and Domchek, Susan M}},
  issn         = {{1527-7755}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{134--244}},
  publisher    = {{American Society of Clinical Oncology}},
  series       = {{Journal of Clinical Oncology}},
  title        = {{Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation.}},
  url          = {{http://dx.doi.org/10.1200/JCO.2014.56.2728}},
  doi          = {{10.1200/JCO.2014.56.2728}},
  volume       = {{33}},
  year         = {{2015}},
}