Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Measurement of transplanted pancreatic volume using computed tomography : reliability by intra- and inter-observer variability

Lundqvist, Eva ; Segelsjö, Monica ; Andersson, Anna ; Magnusson, Anders and Biglarnia, Ali-Reza LU (2012) In Acta radiologica (Stockholm, Sweden : 1987) 53(9). p.72-966
Abstract

BACKGROUND: Unlike other solid organ transplants, pancreas allografts can undergo a substantial decrease in baseline volume after transplantation. This phenomenon has not been well characterized, as there are insufficient data on reliable and reproducible volume assessments. We hypothesized that characterization of pancreatic volume by means of computed tomography (CT) could be a useful method for clinical follow-up in pancreas transplant patients.

PURPOSE: To evaluate the feasibility and reliability of pancreatic volume assessment using CT scan in transplanted patients.

MATERIAL AND METHODS: CT examinations were performed on 21 consecutive patients undergoing pancreas transplantation. Volume measurements were carried out by... (More)

BACKGROUND: Unlike other solid organ transplants, pancreas allografts can undergo a substantial decrease in baseline volume after transplantation. This phenomenon has not been well characterized, as there are insufficient data on reliable and reproducible volume assessments. We hypothesized that characterization of pancreatic volume by means of computed tomography (CT) could be a useful method for clinical follow-up in pancreas transplant patients.

PURPOSE: To evaluate the feasibility and reliability of pancreatic volume assessment using CT scan in transplanted patients.

MATERIAL AND METHODS: CT examinations were performed on 21 consecutive patients undergoing pancreas transplantation. Volume measurements were carried out by two observers tracing the pancreatic contours in all slices. The observers performed the measurements twice for each patient. Differences in volume measurement were used to evaluate intra- and inter-observer variability.

RESULTS: The intra-observer variability for the pancreatic volume measurements of Observers 1 and 2 was found to be in almost perfect agreement, with an intraclass correlation coefficient (ICC) of 0.90 (0.77-0.96) and 0.99 (0.98-1.0), respectively. Regarding inter-observer validity, the ICCs for the first and second measurements were 0.90 (range, 0.77-0.96) and 0.95 (range, 0.85-0.98), respectively.

CONCLUSION: CT volumetry is a reliable and reproducible method for measurement of transplanted pancreatic volume.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Adult, Contrast Media/administration & dosage, Feasibility Studies, Female, Humans, Image Processing, Computer-Assisted, Iopamidol/administration & dosage, Male, Middle Aged, Organ Size, Pancreas/diagnostic imaging, Pancreas Transplantation, Prospective Studies, Reproducibility of Results, Tomography, X-Ray Computed/methods
in
Acta radiologica (Stockholm, Sweden : 1987)
volume
53
issue
9
pages
72 - 966
publisher
SAGE Publications
external identifiers
  • pmid:23002143
ISSN
1600-0455
DOI
10.1258/ar.2012.120317
language
English
LU publication?
no
id
3396f7ac-0953-4ffe-913b-cb41fb6b77fe
date added to LUP
2025-12-17 14:18:17
date last changed
2025-12-17 14:41:01
@article{3396f7ac-0953-4ffe-913b-cb41fb6b77fe,
  abstract     = {{<p>BACKGROUND: Unlike other solid organ transplants, pancreas allografts can undergo a substantial decrease in baseline volume after transplantation. This phenomenon has not been well characterized, as there are insufficient data on reliable and reproducible volume assessments. We hypothesized that characterization of pancreatic volume by means of computed tomography (CT) could be a useful method for clinical follow-up in pancreas transplant patients.</p><p>PURPOSE: To evaluate the feasibility and reliability of pancreatic volume assessment using CT scan in transplanted patients.</p><p>MATERIAL AND METHODS: CT examinations were performed on 21 consecutive patients undergoing pancreas transplantation. Volume measurements were carried out by two observers tracing the pancreatic contours in all slices. The observers performed the measurements twice for each patient. Differences in volume measurement were used to evaluate intra- and inter-observer variability.</p><p>RESULTS: The intra-observer variability for the pancreatic volume measurements of Observers 1 and 2 was found to be in almost perfect agreement, with an intraclass correlation coefficient (ICC) of 0.90 (0.77-0.96) and 0.99 (0.98-1.0), respectively. Regarding inter-observer validity, the ICCs for the first and second measurements were 0.90 (range, 0.77-0.96) and 0.95 (range, 0.85-0.98), respectively.</p><p>CONCLUSION: CT volumetry is a reliable and reproducible method for measurement of transplanted pancreatic volume.</p>}},
  author       = {{Lundqvist, Eva and Segelsjö, Monica and Andersson, Anna and Magnusson, Anders and Biglarnia, Ali-Reza}},
  issn         = {{1600-0455}},
  keywords     = {{Adult; Contrast Media/administration & dosage; Feasibility Studies; Female; Humans; Image Processing, Computer-Assisted; Iopamidol/administration & dosage; Male; Middle Aged; Organ Size; Pancreas/diagnostic imaging; Pancreas Transplantation; Prospective Studies; Reproducibility of Results; Tomography, X-Ray Computed/methods}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{9}},
  pages        = {{72--966}},
  publisher    = {{SAGE Publications}},
  series       = {{Acta radiologica (Stockholm, Sweden : 1987)}},
  title        = {{Measurement of transplanted pancreatic volume using computed tomography : reliability by intra- and inter-observer variability}},
  url          = {{http://dx.doi.org/10.1258/ar.2012.120317}},
  doi          = {{10.1258/ar.2012.120317}},
  volume       = {{53}},
  year         = {{2012}},
}