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Supported liquid membrane extraction of urinary trans, trans-muconic acid, a biomarker for benzene exposure

Norberg, J; Tiruye, D; Mathiasson, Lennart LU and Jönsson, Jan Åke LU (2002) In Journal of Separation Science 25(5-6). p.351-355
Abstract
In this study, sample preparation of urinary trans, trans-muconic acid (tt-MA), a minor metabolite and biomarker of benzene, by means of Supported Liquid Membrane (SLM) extraction has been investigated. The sample extract was automatically transferred on-line to an ion exchange chromatographic column and the analytes were detected using a photodiode array detector. Automation of the system was accomplished using a robotic sample preparation processor integrated into the chromatographic system. Detection limits calculated from the baseline noise was in the sub-ppb range, and quantification of tt-MA is safe down to 10 ppb.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
extraction, supported liquid membrane, benzene exposure, biomarker, muconic acid, urine analysis
in
Journal of Separation Science
volume
25
issue
5-6
pages
351 - 355
publisher
John Wiley & Sons
external identifiers
  • wos:000175209300014
  • scopus:0036250223
ISSN
1615-9314
DOI
10.1002/1615-9314(20020401)25:5/6<351::AID-JSSC351>3.0.CO;2-H
language
English
LU publication?
yes
id
4c81f7e2-c107-4ca6-8387-e7a94272bb2f (old id 339904)
date added to LUP
2007-11-16 14:50:35
date last changed
2017-01-15 03:25:48
@article{4c81f7e2-c107-4ca6-8387-e7a94272bb2f,
  abstract     = {In this study, sample preparation of urinary trans, trans-muconic acid (tt-MA), a minor metabolite and biomarker of benzene, by means of Supported Liquid Membrane (SLM) extraction has been investigated. The sample extract was automatically transferred on-line to an ion exchange chromatographic column and the analytes were detected using a photodiode array detector. Automation of the system was accomplished using a robotic sample preparation processor integrated into the chromatographic system. Detection limits calculated from the baseline noise was in the sub-ppb range, and quantification of tt-MA is safe down to 10 ppb.},
  author       = {Norberg, J and Tiruye, D and Mathiasson, Lennart and Jönsson, Jan Åke},
  issn         = {1615-9314},
  keyword      = {extraction,supported liquid membrane,benzene exposure,biomarker,muconic acid,urine analysis},
  language     = {eng},
  number       = {5-6},
  pages        = {351--355},
  publisher    = {John Wiley & Sons},
  series       = {Journal of Separation Science},
  title        = {Supported liquid membrane extraction of urinary trans, trans-muconic acid, a biomarker for benzene exposure},
  url          = {http://dx.doi.org/10.1002/1615-9314(20020401)25:5/6<351::AID-JSSC351>3.0.CO;2-H},
  volume       = {25},
  year         = {2002},
}