In vitro-uptake of L-Dopa and catecholamines into the epidermal Langerhans cell
(1978) In Acta dermato-venereologica. Supplementum 79. p.31-35- Abstract
- The Langerhans cells are capable of taking up L-dopa and the catecholamines dopamine and noradrenaline when exposed to these substances in vitro. Within the cell L-dopa is found in the cytoplasm as well as in the nucleus, whereas the catecholamines are confined to cytoplasmic granules. The L-dopa uptake is most probably carrier-mediated and the hypothesis is brought forward that L-dopa enters the cell by exchange diffusion. At present little is known about the nature of the amine uptake mechanism.
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- author
- Axelsson, S ; Elofsson, Rolf LU ; Falck, Bengt LU and Sjöborg, Steinar
- organization
- publishing date
- 1978
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta dermato-venereologica. Supplementum
- volume
- 79
- pages
- 31 - 35
- publisher
- Scandinavian University Press
- external identifiers
-
- scopus:0017868569
- ISSN
- 0365-8341
- language
- English
- LU publication?
- yes
- id
- 33c2ce44-ae43-4c7b-89f3-7561ca0ab535
- date added to LUP
- 2016-11-30 16:10:42
- date last changed
- 2021-08-29 04:01:36
@article{33c2ce44-ae43-4c7b-89f3-7561ca0ab535, abstract = {{The Langerhans cells are capable of taking up L-dopa and the catecholamines dopamine and noradrenaline when exposed to these substances in vitro. Within the cell L-dopa is found in the cytoplasm as well as in the nucleus, whereas the catecholamines are confined to cytoplasmic granules. The L-dopa uptake is most probably carrier-mediated and the hypothesis is brought forward that L-dopa enters the cell by exchange diffusion. At present little is known about the nature of the amine uptake mechanism.}}, author = {{Axelsson, S and Elofsson, Rolf and Falck, Bengt and Sjöborg, Steinar}}, issn = {{0365-8341}}, language = {{eng}}, pages = {{31--35}}, publisher = {{Scandinavian University Press}}, series = {{Acta dermato-venereologica. Supplementum}}, title = {{In vitro-uptake of L-Dopa and catecholamines into the epidermal Langerhans cell}}, volume = {{79}}, year = {{1978}}, }