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In vitro-uptake of L-Dopa and catecholamines into the epidermal Langerhans cell

Axelsson, S; Elofsson, Rolf LU ; Falck, Bengt LU and Sjöborg, Steinar (1978) In Acta Dermatovenerologica Supplement 79. p.31-35
Abstract
The Langerhans cells are capable of taking up L-dopa and the catecholamines dopamine and noradrenaline when exposed to these substances in vitro. Within the cell L-dopa is found in the cytoplasm as well as in the nucleus, whereas the catecholamines are confined to cytoplasmic granules. The L-dopa uptake is most probably carrier-mediated and the hypothesis is brought forward that L-dopa enters the cell by exchange diffusion. At present little is known about the nature of the amine uptake mechanism.
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organization
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Contribution to journal
publication status
published
subject
in
Acta Dermatovenerologica Supplement
volume
79
pages
31 - 35
external identifiers
  • scopus:0017868569
language
English
LU publication?
yes
id
33c2ce44-ae43-4c7b-89f3-7561ca0ab535
date added to LUP
2016-11-30 16:10:42
date last changed
2017-08-27 06:30:21
@article{33c2ce44-ae43-4c7b-89f3-7561ca0ab535,
  abstract     = {The Langerhans cells are capable of taking up L-dopa and the catecholamines dopamine and noradrenaline when exposed to these substances in vitro. Within the cell L-dopa is found in the cytoplasm as well as in the nucleus, whereas the catecholamines are confined to cytoplasmic granules. The L-dopa uptake is most probably carrier-mediated and the hypothesis is brought forward that L-dopa enters the cell by exchange diffusion. At present little is known about the nature of the amine uptake mechanism. },
  author       = {Axelsson, S and Elofsson, Rolf and Falck, Bengt and Sjöborg, Steinar},
  language     = {eng},
  pages        = {31--35},
  series       = {Acta Dermatovenerologica Supplement},
  title        = {In vitro-uptake of L-Dopa and catecholamines into the epidermal Langerhans cell},
  volume       = {79},
  year         = {1978},
}