Gold-coated capillary based 2,4-dichlorophenoxyacetic acid chemi-lumincscent assays: possibilities towards multianalysis
(2002) Multianalyte Biosensing Devices Workshop 17(4). p.283-288- Abstract
- The application of gold-coated glass capillaries for the design of a sensitive chemiluminescent immunoassay for 2,4-dichlorophenoxyacetic acid (2,4-D) is reported. The gold coating on the glass capillaries has been partially characterized and its effect on enhancing the signal intensity has been measured. A simple photo-multiplier tube-based photon detector is used for this purpose. At least three times improvement in the signal intensity is observed compared to uncoated glass capillaries, with a consequent improvement in the sensitivity of detection. Using such gold-coated glass capillaries, 2,4-D in the range 10(-9) to 10(-13) mol/l is detectable at a precision of +/-15% (CV%) and a limit of detection of 10(-15) mol/l is achievable. The... (More)
- The application of gold-coated glass capillaries for the design of a sensitive chemiluminescent immunoassay for 2,4-dichlorophenoxyacetic acid (2,4-D) is reported. The gold coating on the glass capillaries has been partially characterized and its effect on enhancing the signal intensity has been measured. A simple photo-multiplier tube-based photon detector is used for this purpose. At least three times improvement in the signal intensity is observed compared to uncoated glass capillaries, with a consequent improvement in the sensitivity of detection. Using such gold-coated glass capillaries, 2,4-D in the range 10(-9) to 10(-13) mol/l is detectable at a precision of +/-15% (CV%) and a limit of detection of 10(-15) mol/l is achievable. The possibility of using such gold-coated capillaries with a portable multianalytical set-up for field studies is also demonstrated. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/341241
- author
- Ramanathan, Kumaran LU ; Dzgoev, Anatoly LU ; Svitel, Juraj LU ; Rees Jönsson, Birgitta LU and Danielsson, Bengt LU
- organization
- publishing date
- 2002
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- pesticides, detection limit, portable multianalytical set-up, precision, capillaries, Au-coated glass capillaries, Au, acid, sensitivity, photo-multiplier tube-based photon detector, signal intensity, glass capillaries, Au coating, sensitive chemiluminescent immunoassay, design, 4-dichlorophenoxyacetic acid chemiluminescent assays, Au-coated capillary based 2, multianalysis, assays
- host publication
- Biosensors and Bioelectronics
- volume
- 17
- issue
- 4
- pages
- 283 - 288
- publisher
- Elsevier
- conference name
- Multianalyte Biosensing Devices Workshop
- conference location
- Athens, Greece
- conference dates
- 2000-04-13 - 2000-04-14
- external identifiers
-
- pmid:11849924
- wos:000174693300005
- scopus:0036179551
- ISSN
- 0956-5663
- DOI
- 10.1016/S0956-5663(01)00296-2
- language
- English
- LU publication?
- yes
- id
- 2b675f1e-2e77-46a2-9499-47f35722897d (old id 341241)
- date added to LUP
- 2016-04-01 15:27:32
- date last changed
- 2022-02-27 07:03:36
@inproceedings{2b675f1e-2e77-46a2-9499-47f35722897d,
abstract = {{The application of gold-coated glass capillaries for the design of a sensitive chemiluminescent immunoassay for 2,4-dichlorophenoxyacetic acid (2,4-D) is reported. The gold coating on the glass capillaries has been partially characterized and its effect on enhancing the signal intensity has been measured. A simple photo-multiplier tube-based photon detector is used for this purpose. At least three times improvement in the signal intensity is observed compared to uncoated glass capillaries, with a consequent improvement in the sensitivity of detection. Using such gold-coated glass capillaries, 2,4-D in the range 10(-9) to 10(-13) mol/l is detectable at a precision of +/-15% (CV%) and a limit of detection of 10(-15) mol/l is achievable. The possibility of using such gold-coated capillaries with a portable multianalytical set-up for field studies is also demonstrated.}},
author = {{Ramanathan, Kumaran and Dzgoev, Anatoly and Svitel, Juraj and Rees Jönsson, Birgitta and Danielsson, Bengt}},
booktitle = {{Biosensors and Bioelectronics}},
issn = {{0956-5663}},
keywords = {{pesticides; detection limit; portable multianalytical set-up; precision; capillaries; Au-coated glass capillaries; Au; acid; sensitivity; photo-multiplier tube-based photon detector; signal intensity; glass capillaries; Au coating; sensitive chemiluminescent immunoassay; design; 4-dichlorophenoxyacetic acid chemiluminescent assays; Au-coated capillary based 2; multianalysis; assays}},
language = {{eng}},
number = {{4}},
pages = {{283--288}},
publisher = {{Elsevier}},
title = {{Gold-coated capillary based 2,4-dichlorophenoxyacetic acid chemi-lumincscent assays: possibilities towards multianalysis}},
url = {{http://dx.doi.org/10.1016/S0956-5663(01)00296-2}},
doi = {{10.1016/S0956-5663(01)00296-2}},
volume = {{17}},
year = {{2002}},
}