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Capillary supply of the tibialis anterior muscle in young, healthy, and moderately active men and women

Porter, MM; Stuart, S; Boij, M and Lexell, Jan LU (2002) In Journal of Applied Physiology 92(4). p.1451-1457
Abstract
Tibialis anterior muscle biopsies from moderately active men and women (21-30 yr; n = 30) were examined to determine potential gender differences in capillarization. The fiber type proportions [type I (T1) similar to73%] were unaffected by gender. The men (M) had significantly (P < 0.001) larger fibers than the women (W), with a greater gender effect for type II (T2) fibers P < 0.001). The M and W had similar capillary densities (CD similar to390 capillaries/mm(2)), but the capillaries-to-fiber ratio (C/F) was higher in the M (M = 2.20 +/- 0.35, W = 1.66 +/- 0.32; P < 0.01). Capillary contacts (CC) were higher in T2 than T1 for the M (P < 0.01), but not W, and M had greater CC (P < 0.001). Both fiber area per capillary... (More)
Tibialis anterior muscle biopsies from moderately active men and women (21-30 yr; n = 30) were examined to determine potential gender differences in capillarization. The fiber type proportions [type I (T1) similar to73%] were unaffected by gender. The men (M) had significantly (P < 0.001) larger fibers than the women (W), with a greater gender effect for type II (T2) fibers P < 0.001). The M and W had similar capillary densities (CD similar to390 capillaries/mm(2)), but the capillaries-to-fiber ratio (C/F) was higher in the M (M = 2.20 +/- 0.35, W = 1.66 +/- 0.32; P < 0.01). Capillary contacts (CC) were higher in T2 than T1 for the M (P < 0.01), but not W, and M had greater CC (P < 0.001). Both fiber area per capillary (FA/C) and fiber perimeter per capillary (FP/C) indicated that T1 fibers had greater capillarization than T2 fibers (P < 0.001). There were no gender differences in T1 FA/C and T2 FA/C or T1 FP/C, but a gender difference existed for T2 FP/C (M = 60.5 +/- 10.9, W = 70.6 +/- 13.4; P < 0.01). The gender difference for C/F could be explained by fiber size; however, the physiological implications of the difference in T2 FP/C remains to be determined. In conclusion, despite gender differences for fiber size, overall, capillarization was similar between the men and women. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
muscle fibers, capillaries, sex factors
in
Journal of Applied Physiology
volume
92
issue
4
pages
1451 - 1457
publisher
American Physiological Society
external identifiers
  • wos:000174572600014
  • pmid:11896009
  • scopus:0036095528
ISSN
1522-1601
DOI
10.1152/japplphysiol.00744.2001
language
English
LU publication?
yes
id
5e31ddd8-d5bf-4678-875c-0dbd49705d1c (old id 341866)
date added to LUP
2007-11-09 12:23:24
date last changed
2017-12-10 03:43:23
@article{5e31ddd8-d5bf-4678-875c-0dbd49705d1c,
  abstract     = {Tibialis anterior muscle biopsies from moderately active men and women (21-30 yr; n = 30) were examined to determine potential gender differences in capillarization. The fiber type proportions [type I (T1) similar to73%] were unaffected by gender. The men (M) had significantly (P &lt; 0.001) larger fibers than the women (W), with a greater gender effect for type II (T2) fibers P &lt; 0.001). The M and W had similar capillary densities (CD similar to390 capillaries/mm(2)), but the capillaries-to-fiber ratio (C/F) was higher in the M (M = 2.20 +/- 0.35, W = 1.66 +/- 0.32; P &lt; 0.01). Capillary contacts (CC) were higher in T2 than T1 for the M (P &lt; 0.01), but not W, and M had greater CC (P &lt; 0.001). Both fiber area per capillary (FA/C) and fiber perimeter per capillary (FP/C) indicated that T1 fibers had greater capillarization than T2 fibers (P &lt; 0.001). There were no gender differences in T1 FA/C and T2 FA/C or T1 FP/C, but a gender difference existed for T2 FP/C (M = 60.5 +/- 10.9, W = 70.6 +/- 13.4; P &lt; 0.01). The gender difference for C/F could be explained by fiber size; however, the physiological implications of the difference in T2 FP/C remains to be determined. In conclusion, despite gender differences for fiber size, overall, capillarization was similar between the men and women.},
  author       = {Porter, MM and Stuart, S and Boij, M and Lexell, Jan},
  issn         = {1522-1601},
  keyword      = {muscle fibers,capillaries,sex factors},
  language     = {eng},
  number       = {4},
  pages        = {1451--1457},
  publisher    = {American Physiological Society},
  series       = {Journal of Applied Physiology},
  title        = {Capillary supply of the tibialis anterior muscle in young, healthy, and moderately active men and women},
  url          = {http://dx.doi.org/10.1152/japplphysiol.00744.2001},
  volume       = {92},
  year         = {2002},
}