Role of extracellular membrane vesicles in intercellular communication of the tumour microenvironment.
(2013) In Biochemical Society Transactions 41(1). p.273-276- Abstract
- Over the last few decades, extensive studies by several groups have introduced the concept of cell-derived secreted extracellular membrane vesicles as carriers of complex molecular information. Owing to their pleiotropic biological effects and involvement in a wide variety of biological processes, extracellular membrane vesicles have been implicated in physiological as well as pathological events, including tumour development and metastasis. In the present review, we discuss the role of secreted membrane vesicles in intercellular communication with a focus on tumour biology. Of particular interest is the potential role of extracellular vesicles as orchestrators of common features of the malignant tumour microenvironment, e.g. coagulation... (More)
- Over the last few decades, extensive studies by several groups have introduced the concept of cell-derived secreted extracellular membrane vesicles as carriers of complex molecular information. Owing to their pleiotropic biological effects and involvement in a wide variety of biological processes, extracellular membrane vesicles have been implicated in physiological as well as pathological events, including tumour development and metastasis. In the present review, we discuss the role of secreted membrane vesicles in intercellular communication with a focus on tumour biology. Of particular interest is the potential role of extracellular vesicles as orchestrators of common features of the malignant tumour microenvironment, e.g. coagulation activation and angiogenesis. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3438216
- author
- Svensson, Katrin LU and Belting, Mattias LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Biochemical Society Transactions
- volume
- 41
- issue
- 1
- pages
- 273 - 276
- publisher
- Biochemical Society
- external identifiers
-
- wos:000314222900045
- pmid:23356296
- scopus:84873150410
- ISSN
- 0300-5127
- DOI
- 10.1042/BST20120248
- language
- English
- LU publication?
- yes
- id
- 96707640-b7a1-432f-8181-f0302f947be6 (old id 3438216)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23356296?dopt=Abstract
- date added to LUP
- 2016-04-04 08:34:46
- date last changed
- 2022-01-29 03:37:37
@article{96707640-b7a1-432f-8181-f0302f947be6, abstract = {{Over the last few decades, extensive studies by several groups have introduced the concept of cell-derived secreted extracellular membrane vesicles as carriers of complex molecular information. Owing to their pleiotropic biological effects and involvement in a wide variety of biological processes, extracellular membrane vesicles have been implicated in physiological as well as pathological events, including tumour development and metastasis. In the present review, we discuss the role of secreted membrane vesicles in intercellular communication with a focus on tumour biology. Of particular interest is the potential role of extracellular vesicles as orchestrators of common features of the malignant tumour microenvironment, e.g. coagulation activation and angiogenesis.}}, author = {{Svensson, Katrin and Belting, Mattias}}, issn = {{0300-5127}}, language = {{eng}}, number = {{1}}, pages = {{273--276}}, publisher = {{Biochemical Society}}, series = {{Biochemical Society Transactions}}, title = {{Role of extracellular membrane vesicles in intercellular communication of the tumour microenvironment.}}, url = {{http://dx.doi.org/10.1042/BST20120248}}, doi = {{10.1042/BST20120248}}, volume = {{41}}, year = {{2013}}, }