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Single-stage multidisciplinary surgical repair of a secondary aortoesophageal fistula : A technical case report with 3-year uneventful follow-up

Zeyara, Adam LU orcid ; Al Saedi, Firas ; Fransson, Torbjörn LU orcid ; Nozohoor, Shahab LU orcid ; Ahl, Jonas LU ; Wierup, Per LU and Johansson, Jan LU (2026) In JTCVS Techniques 38.
Abstract

OBJECTIVE: Secondary aortoesophageal fistula (AEF) after thoracic endovascular aortic repair (TEVAR) is a rare but life-threatening complication. Definitive treatment guidelines are lacking, and surgical management has traditionally relied on staged procedures. Reports of successful single-stage repair with long-term follow-up remain scarce. This case report aims to describe the workup, surgical strategy, and long-term outcomes of a single-stage multidisciplinary repair of secondary AEF after TEVAR.

METHODS: We report the case of a 75-year-old man who presented with recurrent infectious episodes 9 years after TEVAR. A secondary AEF was diagnosed in May 2022. After the failure of conservative treatment (ie, antibiotic therapy) over... (More)

OBJECTIVE: Secondary aortoesophageal fistula (AEF) after thoracic endovascular aortic repair (TEVAR) is a rare but life-threatening complication. Definitive treatment guidelines are lacking, and surgical management has traditionally relied on staged procedures. Reports of successful single-stage repair with long-term follow-up remain scarce. This case report aims to describe the workup, surgical strategy, and long-term outcomes of a single-stage multidisciplinary repair of secondary AEF after TEVAR.

METHODS: We report the case of a 75-year-old man who presented with recurrent infectious episodes 9 years after TEVAR. A secondary AEF was diagnosed in May 2022. After the failure of conservative treatment (ie, antibiotic therapy) over approximately 1 year, a multidisciplinary team recommended definitive surgery. In April 2023, a single-stage repair was performed, comprising complete resection of the infected stent graft, in situ replacement with an antibiotic-soaked prosthesis, primary esophageal repair, and interposition of a pedicled latissimus dorsi muscle flap.

RESULTS: The patient was discharged on postoperative day 30. Three-year follow-up demonstrated sustained remission with normalized inflammatory markers and no evidence of graft reinfection.

CONCLUSIONS: In this case report, a single-stage multidisciplinary surgical repair of secondary AEF after TEVAR yielded durable infection control and favorable long-term outcomes. Careful patient selection within a multidisciplinary team, meticulous surgical planning, and close postoperative infectious disease follow-up are essential. Three-year follow-up demonstrated sustained remission with normalized inflammatory markers and no evidence of graft reinfection.

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author
; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
JTCVS Techniques
volume
38
article number
102417
publisher
Elsevier
external identifiers
  • pmid:42577133
  • scopus:105040940057
ISSN
2666-2507
DOI
10.1016/j.xjtc.2026.102417
language
English
LU publication?
no
additional info
© 2026 The Author(s).
id
34d85878-c048-4b0f-a4e4-efa3b55b2a4d
date added to LUP
2026-08-24 08:45:27
date last changed
2026-08-25 04:01:14
@article{34d85878-c048-4b0f-a4e4-efa3b55b2a4d,
  abstract     = {{<p>OBJECTIVE: Secondary aortoesophageal fistula (AEF) after thoracic endovascular aortic repair (TEVAR) is a rare but life-threatening complication. Definitive treatment guidelines are lacking, and surgical management has traditionally relied on staged procedures. Reports of successful single-stage repair with long-term follow-up remain scarce. This case report aims to describe the workup, surgical strategy, and long-term outcomes of a single-stage multidisciplinary repair of secondary AEF after TEVAR.</p><p>METHODS: We report the case of a 75-year-old man who presented with recurrent infectious episodes 9 years after TEVAR. A secondary AEF was diagnosed in May 2022. After the failure of conservative treatment (ie, antibiotic therapy) over approximately 1 year, a multidisciplinary team recommended definitive surgery. In April 2023, a single-stage repair was performed, comprising complete resection of the infected stent graft, in situ replacement with an antibiotic-soaked prosthesis, primary esophageal repair, and interposition of a pedicled latissimus dorsi muscle flap.</p><p>RESULTS: The patient was discharged on postoperative day 30. Three-year follow-up demonstrated sustained remission with normalized inflammatory markers and no evidence of graft reinfection.</p><p>CONCLUSIONS: In this case report, a single-stage multidisciplinary surgical repair of secondary AEF after TEVAR yielded durable infection control and favorable long-term outcomes. Careful patient selection within a multidisciplinary team, meticulous surgical planning, and close postoperative infectious disease follow-up are essential. Three-year follow-up demonstrated sustained remission with normalized inflammatory markers and no evidence of graft reinfection.</p>}},
  author       = {{Zeyara, Adam and Al Saedi, Firas and Fransson, Torbjörn and Nozohoor, Shahab and Ahl, Jonas and Wierup, Per and Johansson, Jan}},
  issn         = {{2666-2507}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{JTCVS Techniques}},
  title        = {{Single-stage multidisciplinary surgical repair of a secondary aortoesophageal fistula : A technical case report with 3-year uneventful follow-up}},
  url          = {{http://dx.doi.org/10.1016/j.xjtc.2026.102417}},
  doi          = {{10.1016/j.xjtc.2026.102417}},
  volume       = {{38}},
  year         = {{2026}},
}