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Fat quantification using multiecho sequences with bipolar gradients: Investigation of accuracy and noise performance.

Peterson, Pernilla LU and Månsson, Sven LU (2014) In Magnetic Resonance in Medicine 71(1). p.219-229
Abstract
PURPOSE: To investigate the accuracy and noise performance of fat quantification with multiple gradient-echo images acquired using bipolar read-out gradients and compare them with those of the well-established unipolar technique. THEORY: The bipolar read-out technique induces phase and amplitude errors caused by gradient delays, eddy currents, and frequency-dependent coil sensitivity. In this study, these errors were corrected for jointly with the fat/water separation by modeling the impact of these effects on the signal. This approach did not require acquisition of reference data or modification of the pulse sequence. METHODS: Simulations and a phantom experiment were used to investigate the accuracy and noise performance of the technique... (More)
PURPOSE: To investigate the accuracy and noise performance of fat quantification with multiple gradient-echo images acquired using bipolar read-out gradients and compare them with those of the well-established unipolar technique. THEORY: The bipolar read-out technique induces phase and amplitude errors caused by gradient delays, eddy currents, and frequency-dependent coil sensitivity. In this study, these errors were corrected for jointly with the fat/water separation by modeling the impact of these effects on the signal. This approach did not require acquisition of reference data or modification of the pulse sequence. METHODS: Simulations and a phantom experiment were used to investigate the accuracy and noise performance of the technique and compare them with those of a well-established technique using unipolar read-out gradients. Also, the in vivo feasibility was demonstrated for abdominal applications. RESULTS: The phantom experiment demonstrated similar accuracy of the bipolar and unipolar fat quantification techniques. In addition, the noise performance was shown not to be affected by the added estimations of the phase and amplitude errors for most inter-echo times. CONCLUSION: The bipolar technique was found to provide accurate fat quantification with noise performance similar to the unipolar technique given an appropriate choice of inter-echo time. Magn Reson Med, 2013. © 2013 Wiley Periodicals, Inc. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Magnetic Resonance in Medicine
volume
71
issue
1
pages
219 - 229
publisher
Wiley Online Library
external identifiers
  • wos:000328580300024
  • pmid:23412971
  • scopus:84890793492
ISSN
1522-2594
DOI
10.1002/mrm.24657
language
English
LU publication?
yes
id
68aaf102-04f9-4b81-af94-9d5d99469077 (old id 3559724)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23412971?dopt=Abstract
date added to LUP
2013-03-04 13:38:27
date last changed
2017-10-01 03:01:02
@article{68aaf102-04f9-4b81-af94-9d5d99469077,
  abstract     = {PURPOSE: To investigate the accuracy and noise performance of fat quantification with multiple gradient-echo images acquired using bipolar read-out gradients and compare them with those of the well-established unipolar technique. THEORY: The bipolar read-out technique induces phase and amplitude errors caused by gradient delays, eddy currents, and frequency-dependent coil sensitivity. In this study, these errors were corrected for jointly with the fat/water separation by modeling the impact of these effects on the signal. This approach did not require acquisition of reference data or modification of the pulse sequence. METHODS: Simulations and a phantom experiment were used to investigate the accuracy and noise performance of the technique and compare them with those of a well-established technique using unipolar read-out gradients. Also, the in vivo feasibility was demonstrated for abdominal applications. RESULTS: The phantom experiment demonstrated similar accuracy of the bipolar and unipolar fat quantification techniques. In addition, the noise performance was shown not to be affected by the added estimations of the phase and amplitude errors for most inter-echo times. CONCLUSION: The bipolar technique was found to provide accurate fat quantification with noise performance similar to the unipolar technique given an appropriate choice of inter-echo time. Magn Reson Med, 2013. © 2013 Wiley Periodicals, Inc.},
  author       = {Peterson, Pernilla and Månsson, Sven},
  issn         = {1522-2594},
  language     = {eng},
  number       = {1},
  pages        = {219--229},
  publisher    = {Wiley Online Library},
  series       = {Magnetic Resonance in Medicine},
  title        = {Fat quantification using multiecho sequences with bipolar gradients: Investigation of accuracy and noise performance.},
  url          = {http://dx.doi.org/10.1002/mrm.24657},
  volume       = {71},
  year         = {2014},
}