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Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes

Bjerre, Troels ; Crijns, Sjoerd ; Rosenschöld, Per Munck Af LU orcid ; Aznar, Marianne ; Specht, Lena ; Larsen, Rasmus and Keall, Paul (2013) In Physics in Medicine and Biology 58(14). p.4943-4950
Abstract

The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration... (More)

The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney. Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used for online tracking of soft-tissue target volumes.

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author
; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Physics in Medicine and Biology
volume
58
issue
14
pages
4943 - 4950
publisher
IOP Publishing
external identifiers
  • pmid:23807514
  • scopus:84879974927
ISSN
0031-9155
DOI
10.1088/0031-9155/58/14/4943
language
English
LU publication?
no
id
355d38a8-e2c6-49f6-8494-03d51959c423
date added to LUP
2023-07-19 17:14:39
date last changed
2024-04-20 00:49:50
@article{355d38a8-e2c6-49f6-8494-03d51959c423,
  abstract     = {{<p>The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney. Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used for online tracking of soft-tissue target volumes.</p>}},
  author       = {{Bjerre, Troels and Crijns, Sjoerd and Rosenschöld, Per Munck Af and Aznar, Marianne and Specht, Lena and Larsen, Rasmus and Keall, Paul}},
  issn         = {{0031-9155}},
  language     = {{eng}},
  month        = {{07}},
  number       = {{14}},
  pages        = {{4943--4950}},
  publisher    = {{IOP Publishing}},
  series       = {{Physics in Medicine and Biology}},
  title        = {{Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes}},
  url          = {{http://dx.doi.org/10.1088/0031-9155/58/14/4943}},
  doi          = {{10.1088/0031-9155/58/14/4943}},
  volume       = {{58}},
  year         = {{2013}},
}