Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes
(2013) In Physics in Medicine and Biology 58(14). p.4943-4950- Abstract
The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration... (More)
The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney. Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used for online tracking of soft-tissue target volumes.
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- author
- Bjerre, Troels ; Crijns, Sjoerd ; Rosenschöld, Per Munck Af LU ; Aznar, Marianne ; Specht, Lena ; Larsen, Rasmus and Keall, Paul
- publishing date
- 2013-07-21
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Physics in Medicine and Biology
- volume
- 58
- issue
- 14
- pages
- 4943 - 4950
- publisher
- IOP Publishing
- external identifiers
-
- pmid:23807514
- scopus:84879974927
- ISSN
- 0031-9155
- DOI
- 10.1088/0031-9155/58/14/4943
- language
- English
- LU publication?
- no
- id
- 355d38a8-e2c6-49f6-8494-03d51959c423
- date added to LUP
- 2023-07-19 17:14:39
- date last changed
- 2024-04-20 00:49:50
@article{355d38a8-e2c6-49f6-8494-03d51959c423, abstract = {{<p>The introduction of integrated MRI-radiation therapy systems will offer live intra-fraction imaging. We propose a feasible low-latency multi-plane MRI-linac guidance strategy. In this work we demonstrate how interleaved acquired, orthogonal cine-MRI planes can be used for low-latency tracking of the 3D trajectory of a soft-tissue target structure. The proposed strategy relies on acquiring a pre-treatment 3D breath-hold scan, extracting a 3D target template and performing template matching between this 3D template and pairs of orthogonal 2D cine-MRI planes intersecting the target motion path. For a 60 s free-breathing series of orthogonal cine-MRI planes, we demonstrate that the method was capable of accurately tracking the respiration related 3D motion of the left kidney. Quantitative evaluation of the method using a dataset designed for this purpose revealed a translational error of 1.15 mm for a translation of 39.9 mm. We have demonstrated how interleaved acquired, orthogonal cine-MRI planes can be used for online tracking of soft-tissue target volumes.</p>}}, author = {{Bjerre, Troels and Crijns, Sjoerd and Rosenschöld, Per Munck Af and Aznar, Marianne and Specht, Lena and Larsen, Rasmus and Keall, Paul}}, issn = {{0031-9155}}, language = {{eng}}, month = {{07}}, number = {{14}}, pages = {{4943--4950}}, publisher = {{IOP Publishing}}, series = {{Physics in Medicine and Biology}}, title = {{Three-dimensional MRI-linac intra-fraction guidance using multiple orthogonal cine-MRI planes}}, url = {{http://dx.doi.org/10.1088/0031-9155/58/14/4943}}, doi = {{10.1088/0031-9155/58/14/4943}}, volume = {{58}}, year = {{2013}}, }