High prevalence of ascending aortic dilation in adults with repaired coarctation of the aorta
(2021) In Cardiology in the Young 31(6). p.992-997- Abstract
Background: Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients. Methods and results: From the national register of congenital heart disease, 165 adult patients (≥ 18 years old) with repaired coarctation of the aorta, and echocardiographic data on aortic dimensions, were identified (61.2% male, mean age 35.8 ± 14.5 years). Aortic dilation (aortic diameters > 2 SD above reference mean) was found in 55 (33.3%) of the 165 included patients, and was associated with... (More)
Background: Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients. Methods and results: From the national register of congenital heart disease, 165 adult patients (≥ 18 years old) with repaired coarctation of the aorta, and echocardiographic data on aortic dimensions, were identified (61.2% male, mean age 35.8 ± 14.5 years). Aortic dilation (aortic diameters > 2 SD above reference mean) was found in 55 (33.3%) of the 165 included patients, and was associated with manifest aortic valve disease in univariable logistic regression analysis (OR 2.44, 95% CI [1.23, 4.83]). Conclusions: Aortic dilation is common post-repair of coarctation of the aorta, and is associated with manifest aortic valve disease and thus indirectly with the presence of a bicuspid aortic valve. However, no association was found between aortic dilation and age or blood pressure.
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- author
- Rinnström, Daniel ; Dellborg, Mikael ; Thilén, Ulf LU ; Sörensson, Peder ; Nielsen, Niels Erik ; Christersson, Christina and Johansson, Bengt
- organization
- publishing date
- 2021-06-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- aortic dilation, CoA, GUCH
- in
- Cardiology in the Young
- volume
- 31
- issue
- 6
- pages
- 6 pages
- publisher
- Cambridge University Press
- external identifiers
-
- scopus:85100907687
- pmid:33597051
- ISSN
- 1047-9511
- DOI
- 10.1017/S1047951121000111
- language
- English
- LU publication?
- yes
- id
- 3591e27e-87ca-4daf-9014-c312925de32d
- date added to LUP
- 2021-03-04 13:05:34
- date last changed
- 2024-09-19 17:18:22
@article{3591e27e-87ca-4daf-9014-c312925de32d, abstract = {{<p>Background: Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients. Methods and results: From the national register of congenital heart disease, 165 adult patients (≥ 18 years old) with repaired coarctation of the aorta, and echocardiographic data on aortic dimensions, were identified (61.2% male, mean age 35.8 ± 14.5 years). Aortic dilation (aortic diameters > 2 SD above reference mean) was found in 55 (33.3%) of the 165 included patients, and was associated with manifest aortic valve disease in univariable logistic regression analysis (OR 2.44, 95% CI [1.23, 4.83]). Conclusions: Aortic dilation is common post-repair of coarctation of the aorta, and is associated with manifest aortic valve disease and thus indirectly with the presence of a bicuspid aortic valve. However, no association was found between aortic dilation and age or blood pressure. </p>}}, author = {{Rinnström, Daniel and Dellborg, Mikael and Thilén, Ulf and Sörensson, Peder and Nielsen, Niels Erik and Christersson, Christina and Johansson, Bengt}}, issn = {{1047-9511}}, keywords = {{aortic dilation; CoA; GUCH}}, language = {{eng}}, month = {{06}}, number = {{6}}, pages = {{992--997}}, publisher = {{Cambridge University Press}}, series = {{Cardiology in the Young}}, title = {{High prevalence of ascending aortic dilation in adults with repaired coarctation of the aorta}}, url = {{http://dx.doi.org/10.1017/S1047951121000111}}, doi = {{10.1017/S1047951121000111}}, volume = {{31}}, year = {{2021}}, }