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High prevalence of ascending aortic dilation in adults with repaired coarctation of the aorta

Rinnström, Daniel ; Dellborg, Mikael ; Thilén, Ulf LU ; Sörensson, Peder ; Nielsen, Niels Erik ; Christersson, Christina and Johansson, Bengt (2021) In Cardiology in the Young 31(6). p.992-997
Abstract

Background: Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients. Methods and results: From the national register of congenital heart disease, 165 adult patients (≥ 18 years old) with repaired coarctation of the aorta, and echocardiographic data on aortic dimensions, were identified (61.2% male, mean age 35.8 ± 14.5 years). Aortic dilation (aortic diameters > 2 SD above reference mean) was found in 55 (33.3%) of the 165 included patients, and was associated with... (More)

Background: Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients. Methods and results: From the national register of congenital heart disease, 165 adult patients (≥ 18 years old) with repaired coarctation of the aorta, and echocardiographic data on aortic dimensions, were identified (61.2% male, mean age 35.8 ± 14.5 years). Aortic dilation (aortic diameters > 2 SD above reference mean) was found in 55 (33.3%) of the 165 included patients, and was associated with manifest aortic valve disease in univariable logistic regression analysis (OR 2.44, 95% CI [1.23, 4.83]). Conclusions: Aortic dilation is common post-repair of coarctation of the aorta, and is associated with manifest aortic valve disease and thus indirectly with the presence of a bicuspid aortic valve. However, no association was found between aortic dilation and age or blood pressure.

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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
aortic dilation, CoA, GUCH
in
Cardiology in the Young
volume
31
issue
6
pages
6 pages
publisher
Cambridge University Press
external identifiers
  • scopus:85100907687
  • pmid:33597051
ISSN
1047-9511
DOI
10.1017/S1047951121000111
language
English
LU publication?
yes
id
3591e27e-87ca-4daf-9014-c312925de32d
date added to LUP
2021-03-04 13:05:34
date last changed
2024-07-25 12:32:31
@article{3591e27e-87ca-4daf-9014-c312925de32d,
  abstract     = {{<p>Background: Ascending aortic dilation is a feared complication in adults with repaired coarctation of the aorta, as the condition is associated with life-threatening complications such as aortic dissection and rupture. However, the data are currently limited regarding factors associated with ascending aortic dilation in these patients. Methods and results: From the national register of congenital heart disease, 165 adult patients (≥ 18 years old) with repaired coarctation of the aorta, and echocardiographic data on aortic dimensions, were identified (61.2% male, mean age 35.8 ± 14.5 years). Aortic dilation (aortic diameters &gt; 2 SD above reference mean) was found in 55 (33.3%) of the 165 included patients, and was associated with manifest aortic valve disease in univariable logistic regression analysis (OR 2.44, 95% CI [1.23, 4.83]). Conclusions: Aortic dilation is common post-repair of coarctation of the aorta, and is associated with manifest aortic valve disease and thus indirectly with the presence of a bicuspid aortic valve. However, no association was found between aortic dilation and age or blood pressure. </p>}},
  author       = {{Rinnström, Daniel and Dellborg, Mikael and Thilén, Ulf and Sörensson, Peder and Nielsen, Niels Erik and Christersson, Christina and Johansson, Bengt}},
  issn         = {{1047-9511}},
  keywords     = {{aortic dilation; CoA; GUCH}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{6}},
  pages        = {{992--997}},
  publisher    = {{Cambridge University Press}},
  series       = {{Cardiology in the Young}},
  title        = {{High prevalence of ascending aortic dilation in adults with repaired coarctation of the aorta}},
  url          = {{http://dx.doi.org/10.1017/S1047951121000111}},
  doi          = {{10.1017/S1047951121000111}},
  volume       = {{31}},
  year         = {{2021}},
}