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Interpretation of conventional survival analysis and competing risk analysis : An example of hypertension and prostate cancer

Häggström, Christel ; Stattin, Pär ; Stocks, Tanja LU ; Garmo, Hans ; Holmberg, Lars and Van Hemelrijck, Mieke (2016) In BJU International 118(6). p.850-852
Abstract

Most clinical studies use conventional methods for survival analysis and calculate the risk of the event of interest, however, it is important to understand that the study population is also at risk of competing events, for example death from other causes. Moreover, the risk of competing events may be dependent on the participants' characteristics. Whether competing risks are taken into account or not, is of major importance when interpreting study results.Here, we use a practical example to elucidate the interpretational differences of absolute risk estimates obtained with both conventional methods for survival analysis and competing risk analysis. This article is protected by copyright. All rights reserved.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BJU International
volume
118
issue
6
pages
850 - 852
publisher
Wiley-Blackwell
external identifiers
  • scopus:84995468103
  • wos:000388479100007
  • pmid:27037631
ISSN
1464-4096
DOI
10.1111/bju.13494
language
English
LU publication?
yes
id
35d5472b-c5e4-43a7-80dc-4f7fa5c2292b
date added to LUP
2016-04-27 11:20:18
date last changed
2025-01-12 00:39:13
@article{35d5472b-c5e4-43a7-80dc-4f7fa5c2292b,
  abstract     = {{<p>Most clinical studies use conventional methods for survival analysis and calculate the risk of the event of interest, however, it is important to understand that the study population is also at risk of competing events, for example death from other causes. Moreover, the risk of competing events may be dependent on the participants' characteristics. Whether competing risks are taken into account or not, is of major importance when interpreting study results.Here, we use a practical example to elucidate the interpretational differences of absolute risk estimates obtained with both conventional methods for survival analysis and competing risk analysis. This article is protected by copyright. All rights reserved.</p>}},
  author       = {{Häggström, Christel and Stattin, Pär and Stocks, Tanja and Garmo, Hans and Holmberg, Lars and Van Hemelrijck, Mieke}},
  issn         = {{1464-4096}},
  language     = {{eng}},
  month        = {{03}},
  number       = {{6}},
  pages        = {{850--852}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{BJU International}},
  title        = {{Interpretation of conventional survival analysis and competing risk analysis : An example of hypertension and prostate cancer}},
  url          = {{http://dx.doi.org/10.1111/bju.13494}},
  doi          = {{10.1111/bju.13494}},
  volume       = {{118}},
  year         = {{2016}},
}