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Perioperative autotransfusion and functional coagulation analysis in total hip replacement.

Ekbäck, G; Schött, Ulf LU ; Axelsson, K and Carlberg, M (1995) In Acta Anaesthesiologica Scandinavica 39(3). p.390-395
Abstract
Functional coagulation analyses like Sonoclot and thromboelastography have not been evaluated during perioperative autotransfusion. We have prospectively studied three different transfusion regimes in 45 patients undergoing total hip arthroplasty. Blood losses were replaced either with heterologous erythrocyte concentrate (group I), intra- and postoperative autotransfusion of blood salvaged with cellsaver technique (group II) or predonated autologous erythrocyte concentrates together with salvaged blood (group III). Routine and functional coagulation analyses with a Sonoclot were performed preoperatively, 6 hours postoperatively (6 h), day 1-5 and 10. An early postoperative hypo- and late postoperative hypercoagulative phase could be... (More)
Functional coagulation analyses like Sonoclot and thromboelastography have not been evaluated during perioperative autotransfusion. We have prospectively studied three different transfusion regimes in 45 patients undergoing total hip arthroplasty. Blood losses were replaced either with heterologous erythrocyte concentrate (group I), intra- and postoperative autotransfusion of blood salvaged with cellsaver technique (group II) or predonated autologous erythrocyte concentrates together with salvaged blood (group III). Routine and functional coagulation analyses with a Sonoclot were performed preoperatively, 6 hours postoperatively (6 h), day 1-5 and 10. An early postoperative hypo- and late postoperative hypercoagulative phase could be detected with Sonoclot signs of platelet function and fibrin deposition in all groups. Sonoclot coagulation analyses better correlated to both blood loss and dextran dosage than APTT and platelet count in the routine coagulation analyses. Functional coagulation analysis has a potential use in individualizing plasmasubstitution and thromboprophylaxis regimes during autotransfusion in THR. (Less)
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organization
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published
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in
Acta Anaesthesiologica Scandinavica
volume
39
issue
3
pages
390 - 395
publisher
Wiley-Blackwell
external identifiers
  • pmid:7793222
  • scopus:0028968808
ISSN
0001-5172
language
English
LU publication?
yes
id
315f5ba1-db6e-461f-ae21-3db9d713b2f0 (old id 3634384)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/7793222?dopt=Abstract
date added to LUP
2013-07-02 13:08:12
date last changed
2017-02-05 04:33:20
@article{315f5ba1-db6e-461f-ae21-3db9d713b2f0,
  abstract     = {Functional coagulation analyses like Sonoclot and thromboelastography have not been evaluated during perioperative autotransfusion. We have prospectively studied three different transfusion regimes in 45 patients undergoing total hip arthroplasty. Blood losses were replaced either with heterologous erythrocyte concentrate (group I), intra- and postoperative autotransfusion of blood salvaged with cellsaver technique (group II) or predonated autologous erythrocyte concentrates together with salvaged blood (group III). Routine and functional coagulation analyses with a Sonoclot were performed preoperatively, 6 hours postoperatively (6 h), day 1-5 and 10. An early postoperative hypo- and late postoperative hypercoagulative phase could be detected with Sonoclot signs of platelet function and fibrin deposition in all groups. Sonoclot coagulation analyses better correlated to both blood loss and dextran dosage than APTT and platelet count in the routine coagulation analyses. Functional coagulation analysis has a potential use in individualizing plasmasubstitution and thromboprophylaxis regimes during autotransfusion in THR.},
  author       = {Ekbäck, G and Schött, Ulf and Axelsson, K and Carlberg, M},
  issn         = {0001-5172},
  language     = {eng},
  number       = {3},
  pages        = {390--395},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Anaesthesiologica Scandinavica},
  title        = {Perioperative autotransfusion and functional coagulation analysis in total hip replacement.},
  volume       = {39},
  year         = {1995},
}