Quantitative X-ray phase-contrast computed tomography at 82 keV
(2013) In Optics Express 21(4). p.4155-4166- Abstract
- Potential applications of grating-based X-ray phase-contrast imaging are investigated in various fields due to its compatibility with laboratory X-ray sources. So far the method was mainly restricted to X-ray energies below 40 keV, which is too low to examine dense or thick objects, but a routine operation at higher energies is on the brink of realisation. In this study, imaging results obtained at 82 keV are presented. These comprise a test object consisting of well-defined materials for a quantitative analysis and a tooth to translate the findings to a biomedical sample. Measured linear attenuation coefficients mu and electron densities rho(e) are in good agreement with theoretical values. Improved contrast-to-noise ratios were found in... (More)
- Potential applications of grating-based X-ray phase-contrast imaging are investigated in various fields due to its compatibility with laboratory X-ray sources. So far the method was mainly restricted to X-ray energies below 40 keV, which is too low to examine dense or thick objects, but a routine operation at higher energies is on the brink of realisation. In this study, imaging results obtained at 82 keV are presented. These comprise a test object consisting of well-defined materials for a quantitative analysis and a tooth to translate the findings to a biomedical sample. Measured linear attenuation coefficients mu and electron densities rho(e) are in good agreement with theoretical values. Improved contrast-to-noise ratios were found in phase contrast compared to attenuation contrast. The combination of both contrast modalities further enables to simultaneously assess information on density and composition of materials with effective atomic numbers (Z) over tilde > 8. In our biomedical example, we demonstrate the possibility to detect differences in mass density and calcium concentration within teeth. (C) 2013 Optical Society of America (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3651124
- author
- Willner, Marian
; Bech, Martin
LU
; Herzen, Julia ; Zanette, Irene ; Hahn, Dieter ; Kenntner, Johannes ; Mohr, Juergen ; Rack, Alexander ; Weitkamp, Timm and Pfeiffer, Franz
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Optics Express
- volume
- 21
- issue
- 4
- pages
- 4155 - 4166
- publisher
- Optical Society of America
- external identifiers
-
- wos:000315992600022
- scopus:84874526406
- ISSN
- 1094-4087
- DOI
- 10.1364/OE.21.004155
- language
- English
- LU publication?
- yes
- id
- ebf1a5ff-e46c-4e37-84ef-4a57bb547e65 (old id 3651124)
- date added to LUP
- 2016-04-01 14:58:02
- date last changed
- 2022-02-04 23:38:33
@article{ebf1a5ff-e46c-4e37-84ef-4a57bb547e65, abstract = {{Potential applications of grating-based X-ray phase-contrast imaging are investigated in various fields due to its compatibility with laboratory X-ray sources. So far the method was mainly restricted to X-ray energies below 40 keV, which is too low to examine dense or thick objects, but a routine operation at higher energies is on the brink of realisation. In this study, imaging results obtained at 82 keV are presented. These comprise a test object consisting of well-defined materials for a quantitative analysis and a tooth to translate the findings to a biomedical sample. Measured linear attenuation coefficients mu and electron densities rho(e) are in good agreement with theoretical values. Improved contrast-to-noise ratios were found in phase contrast compared to attenuation contrast. The combination of both contrast modalities further enables to simultaneously assess information on density and composition of materials with effective atomic numbers (Z) over tilde > 8. In our biomedical example, we demonstrate the possibility to detect differences in mass density and calcium concentration within teeth. (C) 2013 Optical Society of America}}, author = {{Willner, Marian and Bech, Martin and Herzen, Julia and Zanette, Irene and Hahn, Dieter and Kenntner, Johannes and Mohr, Juergen and Rack, Alexander and Weitkamp, Timm and Pfeiffer, Franz}}, issn = {{1094-4087}}, language = {{eng}}, number = {{4}}, pages = {{4155--4166}}, publisher = {{Optical Society of America}}, series = {{Optics Express}}, title = {{Quantitative X-ray phase-contrast computed tomography at 82 keV}}, url = {{http://dx.doi.org/10.1364/OE.21.004155}}, doi = {{10.1364/OE.21.004155}}, volume = {{21}}, year = {{2013}}, }