A case of gonadotropinoma with polycysts as remnants of Rathke's cleft
Berker, M. ; Hazer, Derya LU
and Soylemezoglu, F.
(2010)
In Acta Endocrinologica
6(4).
p.513-520
- Abstract
Context. This is a case of gonadotropinoma presented with Rathke's cleft cyst. Objective. We are presenting a case of gonadotropinoma along with Rathke's cleft cyst which is unique case as being male and symptomatic gonadotropin releasing adenoma. Method. A 51 year old man was referred to our institution for evaluation of impotence and loss of libido. His endocrine screening evaluations revealed hypopituitarism with low levels of blood cortisol and ACTH, and high levels of prolactin. Results. An endonasal transsphenoidal endoscopic approach was performed and upon inspection via endoscope the floor of sella was eroded and following dural incision soft dark colored tumor overflowed through sella. Pathology revealed gonadotropinoma with... (More)
Context. This is a case of gonadotropinoma presented with Rathke's cleft cyst. Objective. We are presenting a case of gonadotropinoma along with Rathke's cleft cyst which is unique case as being male and symptomatic gonadotropin releasing adenoma. Method. A 51 year old man was referred to our institution for evaluation of impotence and loss of libido. His endocrine screening evaluations revealed hypopituitarism with low levels of blood cortisol and ACTH, and high levels of prolactin. Results. An endonasal transsphenoidal endoscopic approach was performed and upon inspection via endoscope the floor of sella was eroded and following dural incision soft dark colored tumor overflowed through sella. Pathology revealed gonadotropinoma with unexpected remnants of Rathke's cleft cyst. Conclusion. Pituitary adenomas and Rathke's cleft cysts have a common embryologic ancestry. Our case was a symptomatic gonadotropinoma consisting of multicystic component which was then demonstrated as Rathke's cleft cyst in pathological work up. This combination may be the result of a coincidence or Rathke's cleft cysts may be the origin of the pituitary adenomas.
(Less)
- author
- Berker, M.
; Hazer, Derya
LU
and Soylemezoglu, F.
- publishing date
- 2010-10
- type
- Contribution to journal
- publication status
- published
- keywords
- Contrast enhancement, Gonadotropinoma, Rathke's cleft cyst, Sphenoid sinus
- in
- Acta Endocrinologica
- volume
- 6
- issue
- 4
- pages
- 513 - 520
- publisher
- Acta Endocrinologica Foundation
- external identifiers
-
- scopus:79960415981
- ISSN
- 1841-0987
- DOI
- 10.4183/aeb.2010.513
- language
- English
- LU publication?
- no
- id
- 367f90c4-284d-44ff-b578-6dd05a417355
- date added to LUP
- 2025-05-11 22:39:02
- date last changed
- 2025-05-13 13:11:33
@article{367f90c4-284d-44ff-b578-6dd05a417355,
abstract = {{<p>Context. This is a case of gonadotropinoma presented with Rathke's cleft cyst. Objective. We are presenting a case of gonadotropinoma along with Rathke's cleft cyst which is unique case as being male and symptomatic gonadotropin releasing adenoma. Method. A 51 year old man was referred to our institution for evaluation of impotence and loss of libido. His endocrine screening evaluations revealed hypopituitarism with low levels of blood cortisol and ACTH, and high levels of prolactin. Results. An endonasal transsphenoidal endoscopic approach was performed and upon inspection via endoscope the floor of sella was eroded and following dural incision soft dark colored tumor overflowed through sella. Pathology revealed gonadotropinoma with unexpected remnants of Rathke's cleft cyst. Conclusion. Pituitary adenomas and Rathke's cleft cysts have a common embryologic ancestry. Our case was a symptomatic gonadotropinoma consisting of multicystic component which was then demonstrated as Rathke's cleft cyst in pathological work up. This combination may be the result of a coincidence or Rathke's cleft cysts may be the origin of the pituitary adenomas.</p>}},
author = {{Berker, M. and Hazer, Derya and Soylemezoglu, F.}},
issn = {{1841-0987}},
keywords = {{Contrast enhancement; Gonadotropinoma; Rathke's cleft cyst; Sphenoid sinus}},
language = {{eng}},
number = {{4}},
pages = {{513--520}},
publisher = {{Acta Endocrinologica Foundation}},
series = {{Acta Endocrinologica}},
title = {{A case of gonadotropinoma with polycysts as remnants of Rathke's cleft}},
url = {{http://dx.doi.org/10.4183/aeb.2010.513}},
doi = {{10.4183/aeb.2010.513}},
volume = {{6}},
year = {{2010}},
}