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End-of-life treatments in pediatric patients at a government tertiary cancer center in India

Jacob, Jean ; Matharu, Jaskirt K. ; Palat, Gayatri ; Sinha, Sudha ; Brun, Eva LU ; Wiebe, Thomas LU and Segerlantz, Mikael LU (2018) In Journal of Palliative Medicine 21(7). p.907-912
Abstract

Aim: The primary objective of this study was to describe demographics and end-of-life treatments of children with cancer at a government tertiary cancer center in India. Methods: A retrospective review was undertaken of medical charts of all children younger than 18 years, who died as inpatients while undergoing treatment at the pediatric oncology department between April and September 2016. Data were collected on demographics, diagnosis, treatments, survival, palliative care involvement, and symptoms at end of life. Results: There were 44 pediatric oncology patients who died in the hospital during the study period. The most frequent diagnoses were hematological malignancies (n = 29). Tumor-specific treatment was given to 38/44 (86%)... (More)

Aim: The primary objective of this study was to describe demographics and end-of-life treatments of children with cancer at a government tertiary cancer center in India. Methods: A retrospective review was undertaken of medical charts of all children younger than 18 years, who died as inpatients while undergoing treatment at the pediatric oncology department between April and September 2016. Data were collected on demographics, diagnosis, treatments, survival, palliative care involvement, and symptoms at end of life. Results: There were 44 pediatric oncology patients who died in the hospital during the study period. The most frequent diagnoses were hematological malignancies (n = 29). Tumor-specific treatment was given to 38/44 (86%) patients in the last 30 days of life, and 13 patients in the last day of life or 1 day before. Of all deaths, 23/44 (52%) occurred within 30 days of admission to the pediatric ward and 34/44 (77%) within 90 days. Of the 44 patients, 25 (57%) were referred to palliative care. The median number of days between referral and death was 14 (0-78) days. Frequent symptoms documented were bleeding (11/44), dyspnea (10/44), pain (7/44), seizures (7/44), and delirium (5/44), with each patient having one or more of these symptoms. Only patients with a palliative care referral received opioid analgesics or benzodiazepines at the end of life. Conclusions: This study highlights the demographics of suffering, death, and end-of-life care in children with cancer at a government tertiary cancer center in India.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cancer, children, end-of-life care, palliative care
in
Journal of Palliative Medicine
volume
21
issue
7
pages
907 - 912
publisher
Mary Ann Liebert, Inc.
external identifiers
  • pmid:29649402
  • scopus:85049569492
ISSN
1096-6218
DOI
10.1089/jpm.2017.0632
language
English
LU publication?
yes
id
369134f2-9931-49f6-8547-ef98f590884e
date added to LUP
2018-07-23 14:06:35
date last changed
2021-10-06 04:00:29
@article{369134f2-9931-49f6-8547-ef98f590884e,
  abstract     = {<p>Aim: The primary objective of this study was to describe demographics and end-of-life treatments of children with cancer at a government tertiary cancer center in India. Methods: A retrospective review was undertaken of medical charts of all children younger than 18 years, who died as inpatients while undergoing treatment at the pediatric oncology department between April and September 2016. Data were collected on demographics, diagnosis, treatments, survival, palliative care involvement, and symptoms at end of life. Results: There were 44 pediatric oncology patients who died in the hospital during the study period. The most frequent diagnoses were hematological malignancies (n = 29). Tumor-specific treatment was given to 38/44 (86%) patients in the last 30 days of life, and 13 patients in the last day of life or 1 day before. Of all deaths, 23/44 (52%) occurred within 30 days of admission to the pediatric ward and 34/44 (77%) within 90 days. Of the 44 patients, 25 (57%) were referred to palliative care. The median number of days between referral and death was 14 (0-78) days. Frequent symptoms documented were bleeding (11/44), dyspnea (10/44), pain (7/44), seizures (7/44), and delirium (5/44), with each patient having one or more of these symptoms. Only patients with a palliative care referral received opioid analgesics or benzodiazepines at the end of life. Conclusions: This study highlights the demographics of suffering, death, and end-of-life care in children with cancer at a government tertiary cancer center in India.</p>},
  author       = {Jacob, Jean and Matharu, Jaskirt K. and Palat, Gayatri and Sinha, Sudha and Brun, Eva and Wiebe, Thomas and Segerlantz, Mikael},
  issn         = {1096-6218},
  language     = {eng},
  month        = {07},
  number       = {7},
  pages        = {907--912},
  publisher    = {Mary Ann Liebert, Inc.},
  series       = {Journal of Palliative Medicine},
  title        = {End-of-life treatments in pediatric patients at a government tertiary cancer center in India},
  url          = {http://dx.doi.org/10.1089/jpm.2017.0632},
  doi          = {10.1089/jpm.2017.0632},
  volume       = {21},
  year         = {2018},
}