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A novel knee joint model in FEBio with inhomogeneous fibril-reinforced biphasic cartilage simulating tissue mechanical responses during gait : data from the osteoarthritis initiative

Paz, Alexander ; Orozco, Gustavo A LU ; Tanska, Petri ; García, José J ; Korhonen, Rami K and Mononen, Mika E (2023) In Computer Methods in Biomechanics and Biomedical Engineering 26(11). p.1353-1367
Abstract

We developed a novel knee joint model in FEBio to simulate walking. Knee cartilage was modeled using a fibril-reinforced biphasic (FRB) formulation with depth-wise collagen architecture and split-lines to account for cartilage structure. Under axial compression, the knee model with FRB cartilage yielded contact pressures, similar to reported experimental data. Furthermore, gait analysis with FRB cartilage simulated spatial and temporal trends in cartilage fluid pressures, stresses, and strains, comparable to those of a fibril-reinforced poroviscoelastic (FRPVE) material in Abaqus. This knee joint model in FEBio could be used for further studies of knee disorders using physiologically relevant loading.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Biomechanics, transversely isotropic elastic, fibril-reinforced, Poroelastic, Biphasic, finite element analysis, knee joint, cartilage
in
Computer Methods in Biomechanics and Biomedical Engineering
volume
26
issue
11
pages
15 pages
publisher
Taylor & Francis
external identifiers
  • scopus:85137755615
  • pmid:36062938
ISSN
1025-5842
DOI
10.1080/10255842.2022.2117548
language
English
LU publication?
yes
id
36a4dd64-3b49-47f1-a152-7fd0f71ef76c
date added to LUP
2022-09-13 14:20:50
date last changed
2024-04-18 09:28:24
@article{36a4dd64-3b49-47f1-a152-7fd0f71ef76c,
  abstract     = {{<p>We developed a novel knee joint model in FEBio to simulate walking. Knee cartilage was modeled using a fibril-reinforced biphasic (FRB) formulation with depth-wise collagen architecture and split-lines to account for cartilage structure. Under axial compression, the knee model with FRB cartilage yielded contact pressures, similar to reported experimental data. Furthermore, gait analysis with FRB cartilage simulated spatial and temporal trends in cartilage fluid pressures, stresses, and strains, comparable to those of a fibril-reinforced poroviscoelastic (FRPVE) material in Abaqus. This knee joint model in FEBio could be used for further studies of knee disorders using physiologically relevant loading.</p>}},
  author       = {{Paz, Alexander and Orozco, Gustavo A and Tanska, Petri and García, José J and Korhonen, Rami K and Mononen, Mika E}},
  issn         = {{1025-5842}},
  keywords     = {{Biomechanics; transversely isotropic elastic; fibril-reinforced; Poroelastic; Biphasic; finite element analysis; knee joint; cartilage}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{1353--1367}},
  publisher    = {{Taylor & Francis}},
  series       = {{Computer Methods in Biomechanics and Biomedical Engineering}},
  title        = {{A novel knee joint model in FEBio with inhomogeneous fibril-reinforced biphasic cartilage simulating tissue mechanical responses during gait : data from the osteoarthritis initiative}},
  url          = {{http://dx.doi.org/10.1080/10255842.2022.2117548}},
  doi          = {{10.1080/10255842.2022.2117548}},
  volume       = {{26}},
  year         = {{2023}},
}