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Non-obstructive azoospermia and clinical varicocele: therapeutic options.

Elzanaty, Saad LU (2013) In International Urology and Nephrology 45(3). p.669-674
Abstract
Ten to fifteen percent of infertile men are azoospermic, and sixty percent of these men have been classified as having non-obstructive azoospermia (NOA). NOA results from testicular failure, and one of the causes of this is the presence of varicocele. Varicocele is observed in 5-10 % of men with NOA. This review discusses the impact of varicocele repair on semen quality and pregnancy rate among men with NOA. Based on the best available evidence, varicocele repair of men with NOA is associated with an improvement in semen quality and pregnancy rate. Thus, it appears to be an effective therapeutic option for this group of men, particularly for those with a female partner who is younger than 35 years of age, before an assisted reproductive... (More)
Ten to fifteen percent of infertile men are azoospermic, and sixty percent of these men have been classified as having non-obstructive azoospermia (NOA). NOA results from testicular failure, and one of the causes of this is the presence of varicocele. Varicocele is observed in 5-10 % of men with NOA. This review discusses the impact of varicocele repair on semen quality and pregnancy rate among men with NOA. Based on the best available evidence, varicocele repair of men with NOA is associated with an improvement in semen quality and pregnancy rate. Thus, it appears to be an effective therapeutic option for this group of men, particularly for those with a female partner who is younger than 35 years of age, before an assisted reproductive technique (ART) is initiated. Semen cryopreservation is recommended once the patient has spermatozoa in the ejaculate. In addition, varicocele repair seems to improve the rate of spermatozoa recovery in testicular sperm extraction for those who requested ART. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
International Urology and Nephrology
volume
45
issue
3
pages
669 - 674
publisher
Akademiai Kiado
external identifiers
  • wos:000320843400012
  • pmid:23604704
  • scopus:84879504562
ISSN
1573-2584
DOI
10.1007/s11255-013-0443-x
language
English
LU publication?
yes
id
45eb70f5-3d5c-4b94-baf1-54420dca89e4 (old id 3733517)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23604704?dopt=Abstract
date added to LUP
2013-05-04 20:01:05
date last changed
2019-03-08 01:08:05
@article{45eb70f5-3d5c-4b94-baf1-54420dca89e4,
  abstract     = {Ten to fifteen percent of infertile men are azoospermic, and sixty percent of these men have been classified as having non-obstructive azoospermia (NOA). NOA results from testicular failure, and one of the causes of this is the presence of varicocele. Varicocele is observed in 5-10 % of men with NOA. This review discusses the impact of varicocele repair on semen quality and pregnancy rate among men with NOA. Based on the best available evidence, varicocele repair of men with NOA is associated with an improvement in semen quality and pregnancy rate. Thus, it appears to be an effective therapeutic option for this group of men, particularly for those with a female partner who is younger than 35 years of age, before an assisted reproductive technique (ART) is initiated. Semen cryopreservation is recommended once the patient has spermatozoa in the ejaculate. In addition, varicocele repair seems to improve the rate of spermatozoa recovery in testicular sperm extraction for those who requested ART.},
  author       = {Elzanaty, Saad},
  issn         = {1573-2584},
  language     = {eng},
  number       = {3},
  pages        = {669--674},
  publisher    = {Akademiai Kiado},
  series       = {International Urology and Nephrology},
  title        = {Non-obstructive azoospermia and clinical varicocele: therapeutic options.},
  url          = {http://dx.doi.org/10.1007/s11255-013-0443-x},
  volume       = {45},
  year         = {2013},
}