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Comorbidity of Airway Inflammatory Diseases in Chemical and Building-Related Intolerance

Claeson, Anna Sara ; Andersson, Hanna LU orcid ; Wikdahl, Fredrik ; Nyback, Maj Helen and Nordin, Steven (2018) In Journal of Occupational and Environmental Medicine 60(4). p.295-300
Abstract

Objectives: This study investigated comorbidity in chemical intolerance (CI) and building-related intolerance (BRI) with (i) chronic sinusitis, chronic obstructive pulmonary disease, allergic and nonallergic asthma and allergic rhinitis, and (ii) airway inflammatory symptoms. Methods: Data from two population-based questionnaire surveys, the Västerbotten and Österbotten Environmental Health Studies, were used. The participants were categorized as CI or BRI and referents, and binary logistic regression analysis was applied. Results: Prevalence rates for the case groups were 7.2% to 40.0% for diseases and 24.3% to 68.9% for symptoms, whereas adjusted odds ratios (ORs) were 3.4 to 26.1 for diseases and 3.3 to 17.0 for symptoms, all being... (More)

Objectives: This study investigated comorbidity in chemical intolerance (CI) and building-related intolerance (BRI) with (i) chronic sinusitis, chronic obstructive pulmonary disease, allergic and nonallergic asthma and allergic rhinitis, and (ii) airway inflammatory symptoms. Methods: Data from two population-based questionnaire surveys, the Västerbotten and Österbotten Environmental Health Studies, were used. The participants were categorized as CI or BRI and referents, and binary logistic regression analysis was applied. Results: Prevalence rates for the case groups were 7.2% to 40.0% for diseases and 24.3% to 68.9% for symptoms, whereas adjusted odds ratios (ORs) were 3.4 to 26.1 for diseases and 3.3 to 17.0 for symptoms, all being significantly higher than unity. Prevalence rates and ORs were in general higher in BRI than in CI. Conclusion: Inflammatory airway diseases and symptoms are associated with CI and BRI, which encourages further research regarding underlying mechanisms and treatments.

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author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
airway inflammation, allergic asthma, allergic rhinitis, building-related intolerance, chemical intolerance, chronic sinusitis, COPD, nonallergic asthma
in
Journal of Occupational and Environmental Medicine
volume
60
issue
4
pages
6 pages
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:29227362
  • scopus:85045135301
ISSN
1076-2752
DOI
10.1097/JOM.0000000000001249
language
English
LU publication?
no
additional info
Funding Information: From the Department of Psychology, Umeå University, Umeå, Sweden (Dr Claeson, Ms Andersson, Mr Wikdahl, Dr Nordin); and YH Novia/Novia University of Applied Sciences, Vaasa, Finland (Dr Nyback). This study was supported by grants from the Swedish Research Council FOR-MAS (219-2010-1401), the Swedish Research Council for Health, Working Life and Welfare (2011–0396), and the Swedish Foundation for Humanities and Social Sciences (M14-0375:1). Authors Claeson, Andersson, Wikdahl, Nyback, and Nordin have no relation-ships/conditions/circumstances that present potential conflict of interest. The JOEM editorial board and planners have no financial interest related to this research. Address correspondence to: Anna-Sara Claeson, PhD, Department of Psychology, Umeå University, 901 87 Umeå, Sweden (Anna-Sara.Claeson@umu.se). Copyright © 2018 American College of Occupational and Environmental Medicine DOI: 10.1097/JOM.0000000000001249 Publisher Copyright: © 2018 American College of Occupational and Environmental Medicine.
id
378f77b9-0b20-47fc-9e8a-5fff3f9e8f86
date added to LUP
2023-12-05 17:18:50
date last changed
2024-03-21 12:59:57
@article{378f77b9-0b20-47fc-9e8a-5fff3f9e8f86,
  abstract     = {{<p>Objectives: This study investigated comorbidity in chemical intolerance (CI) and building-related intolerance (BRI) with (i) chronic sinusitis, chronic obstructive pulmonary disease, allergic and nonallergic asthma and allergic rhinitis, and (ii) airway inflammatory symptoms. Methods: Data from two population-based questionnaire surveys, the Västerbotten and Österbotten Environmental Health Studies, were used. The participants were categorized as CI or BRI and referents, and binary logistic regression analysis was applied. Results: Prevalence rates for the case groups were 7.2% to 40.0% for diseases and 24.3% to 68.9% for symptoms, whereas adjusted odds ratios (ORs) were 3.4 to 26.1 for diseases and 3.3 to 17.0 for symptoms, all being significantly higher than unity. Prevalence rates and ORs were in general higher in BRI than in CI. Conclusion: Inflammatory airway diseases and symptoms are associated with CI and BRI, which encourages further research regarding underlying mechanisms and treatments.</p>}},
  author       = {{Claeson, Anna Sara and Andersson, Hanna and Wikdahl, Fredrik and Nyback, Maj Helen and Nordin, Steven}},
  issn         = {{1076-2752}},
  keywords     = {{airway inflammation; allergic asthma; allergic rhinitis; building-related intolerance; chemical intolerance; chronic sinusitis; COPD; nonallergic asthma}},
  language     = {{eng}},
  month        = {{04}},
  number       = {{4}},
  pages        = {{295--300}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Journal of Occupational and Environmental Medicine}},
  title        = {{Comorbidity of Airway Inflammatory Diseases in Chemical and Building-Related Intolerance}},
  url          = {{http://dx.doi.org/10.1097/JOM.0000000000001249}},
  doi          = {{10.1097/JOM.0000000000001249}},
  volume       = {{60}},
  year         = {{2018}},
}