Oral lichenoid lesions in two snuff users with contact allergy to carvone
(2024) In Contact Dermatitis 90(1). p.74-78- Abstract
BACKGROUND: Contact allergy to the mint-tasting flavour carvone has been observed in patients with oral lichenoid lesions (OLL). Mint-flavoured products such as toothpaste frequently contain carvone. Snuff is a smokeless tobacco product that is chewed or placed in the mouth rather than smoked. In Sweden, the use of snuff and its flavoured versions is extremely common.
OBJECTIVES: To investigate whether the consumption of mint-flavoured snuff is associated with contact allergy to carvone and subsequently plays a role in the aetiology of OLL.
METHODS: Regarding the two patients, patch testing with snuff pouches was performed. High-performance liquid chromatography and gas chromatography-mass spectrometry analysis were used for... (More)
BACKGROUND: Contact allergy to the mint-tasting flavour carvone has been observed in patients with oral lichenoid lesions (OLL). Mint-flavoured products such as toothpaste frequently contain carvone. Snuff is a smokeless tobacco product that is chewed or placed in the mouth rather than smoked. In Sweden, the use of snuff and its flavoured versions is extremely common.
OBJECTIVES: To investigate whether the consumption of mint-flavoured snuff is associated with contact allergy to carvone and subsequently plays a role in the aetiology of OLL.
METHODS: Regarding the two patients, patch testing with snuff pouches was performed. High-performance liquid chromatography and gas chromatography-mass spectrometry analysis were used for identification of carvone in different snuff samples.
RESULTS: Two patients with OLL were contacted allergic to carvone when patch tested. Both were using mint-flavoured snuffs several hours a day for many years. One patient was contacted allergic to the snuff pouch tested as is. Carvone was detected in the snuff samples of both patients.
CONCLUSIONS: The patients were recommended to avoid the use of mint-flavoured snuffs, toothpaste and foodstuffs. At follow-up 3 months later, the patients had a dramatic clinical improvement of the OLL and oral symptoms. Exposure to mint-flavoured snuffs can be overlooked as a possible aggravating/provoking factor in OLL.
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- author
- Adwa, Usamah ; Antelmi, Annarita LU ; Sukakul, Thanisorn LU ; Dahlin, Jakob LU ; Bruze, Magnus LU and Svedman, Cecilia LU
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Contact Dermatitis
- volume
- 90
- issue
- 1
- pages
- 74 - 78
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85175609621
- pmid:37915267
- ISSN
- 0105-1873
- DOI
- 10.1111/cod.14448
- language
- English
- LU publication?
- no
- additional info
- © 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
- id
- 37b776fd-c2c3-416a-b46c-ad31ae96faa1
- date added to LUP
- 2023-11-20 09:27:52
- date last changed
- 2024-04-18 07:16:33
@article{37b776fd-c2c3-416a-b46c-ad31ae96faa1, abstract = {{<p>BACKGROUND: Contact allergy to the mint-tasting flavour carvone has been observed in patients with oral lichenoid lesions (OLL). Mint-flavoured products such as toothpaste frequently contain carvone. Snuff is a smokeless tobacco product that is chewed or placed in the mouth rather than smoked. In Sweden, the use of snuff and its flavoured versions is extremely common.</p><p>OBJECTIVES: To investigate whether the consumption of mint-flavoured snuff is associated with contact allergy to carvone and subsequently plays a role in the aetiology of OLL.</p><p>METHODS: Regarding the two patients, patch testing with snuff pouches was performed. High-performance liquid chromatography and gas chromatography-mass spectrometry analysis were used for identification of carvone in different snuff samples.</p><p>RESULTS: Two patients with OLL were contacted allergic to carvone when patch tested. Both were using mint-flavoured snuffs several hours a day for many years. One patient was contacted allergic to the snuff pouch tested as is. Carvone was detected in the snuff samples of both patients.</p><p>CONCLUSIONS: The patients were recommended to avoid the use of mint-flavoured snuffs, toothpaste and foodstuffs. At follow-up 3 months later, the patients had a dramatic clinical improvement of the OLL and oral symptoms. Exposure to mint-flavoured snuffs can be overlooked as a possible aggravating/provoking factor in OLL.</p>}}, author = {{Adwa, Usamah and Antelmi, Annarita and Sukakul, Thanisorn and Dahlin, Jakob and Bruze, Magnus and Svedman, Cecilia}}, issn = {{0105-1873}}, language = {{eng}}, number = {{1}}, pages = {{74--78}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Oral lichenoid lesions in two snuff users with contact allergy to carvone}}, url = {{http://dx.doi.org/10.1111/cod.14448}}, doi = {{10.1111/cod.14448}}, volume = {{90}}, year = {{2024}}, }