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Modeling of time domain diffuse Raman spectroscopy in a two-layer medium

Bossi, Alessandro ; Gandolfi, Valerio ; Farina, Andrea ; Bargigia, Ilaria ; Pifferi, Antonio ; Šušnjar, Stefan LU orcid ; Tommasi, Federico ; Fini, Lorenzo ; Kammalamuriyil, Naseer and Martelli, Fabrizio (2025) 13314.
Abstract
A model, based on the solution of two coupled diffusion equations to the excitation and emission wavelengths, respectively, was developed to describe the Raman signal in the time domain in a reflectance configuration in a two-layer medium. The accuracy of the model is characterized by comparison with the results of Monte Carlo simulations. This solver can correctly account for the Raman emitters within the layers and the full wavelength dependence of the optical properties of the layers. The short computation time of this solver makes it suitable for use in reconstructing Raman spectra from time domain measurements at multiple wavelengths.
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
keywords
Diffuse optics, Diffusion equation, Raman scattering, Raman spectra, Monte Carlo simulations
host publication
Proceedings of SPIE : Optical Tomography and Spectroscopy of Tissue XVI - Optical Tomography and Spectroscopy of Tissue XVI
editor
Fantini, Sergio and Taroni, Paola
volume
13314
DOI
10.1117/12.3043395
language
English
LU publication?
no
id
37d59b18-62b3-46b9-900c-a93e55cb0df8
date added to LUP
2025-03-24 17:32:49
date last changed
2025-03-27 08:55:33
@inproceedings{37d59b18-62b3-46b9-900c-a93e55cb0df8,
  abstract     = {{A model, based on the solution of two coupled diffusion equations to the excitation and emission wavelengths, respectively, was developed to describe the Raman signal in the time domain in a reflectance configuration in a two-layer medium. The accuracy of the model is characterized by comparison with the results of Monte Carlo simulations. This solver can correctly account for the Raman emitters within the layers and the full wavelength dependence of the optical properties of the layers. The short computation time of this solver makes it suitable for use in reconstructing Raman spectra from time domain measurements at multiple wavelengths.}},
  author       = {{Bossi, Alessandro and Gandolfi, Valerio and Farina, Andrea and Bargigia, Ilaria and Pifferi, Antonio and Šušnjar, Stefan and Tommasi, Federico and Fini, Lorenzo and Kammalamuriyil, Naseer and Martelli, Fabrizio}},
  booktitle    = {{Proceedings of SPIE : Optical Tomography and Spectroscopy of Tissue XVI}},
  editor       = {{Fantini, Sergio and Taroni, Paola}},
  keywords     = {{Diffuse optics; Diffusion equation; Raman scattering; Raman spectra; Monte Carlo simulations}},
  language     = {{eng}},
  month        = {{03}},
  title        = {{Modeling of time domain diffuse Raman spectroscopy in a two-layer medium}},
  url          = {{http://dx.doi.org/10.1117/12.3043395}},
  doi          = {{10.1117/12.3043395}},
  volume       = {{13314}},
  year         = {{2025}},
}