KinMutBase, a database of human disease-causing protein kinase mutations
Stenberg, KAE ; Riikonen, PT and Vihinen, Mauno LU
(1999)
In Nucleic Acids Research
27(1).
p.362-364
- Abstract
- KinMutBase (http://www.uta.fi/laitokset/imt/KinMutBase. html) is a registry of mutations in human protein kinases related to disorders. Kinases are essential cellular signalling molecules, in which mutations can lead into diseases including, e.g., immunodeficiencies, cancers and endocrine disorders. The first release of KinMutBase contains information for nine protein tyrosine kinases. There are altogether 170 entries representing 273 families and 403 patients. Mutations appear both in conserved hallmark residues of the kinases as well as in non-homologous sites. The KinMutBase WWW pages provide plenty of information, namely mutation statistics and display, clickable sequences with mutations, restriction enzyme patterns and online... (More)
- KinMutBase (http://www.uta.fi/laitokset/imt/KinMutBase. html) is a registry of mutations in human protein kinases related to disorders. Kinases are essential cellular signalling molecules, in which mutations can lead into diseases including, e.g., immunodeficiencies, cancers and endocrine disorders. The first release of KinMutBase contains information for nine protein tyrosine kinases. There are altogether 170 entries representing 273 families and 403 patients. Mutations appear both in conserved hallmark residues of the kinases as well as in non-homologous sites. The KinMutBase WWW pages provide plenty of information, namely mutation statistics and display, clickable sequences with mutations, restriction enzyme patterns and online submission. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3852360
- author
- Stenberg, KAE
; Riikonen, PT
and Vihinen, Mauno
LU
- publishing date
- 1999
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nucleic Acids Research
- volume
- 27
- issue
- 1
- pages
- 362 - 364
- publisher
- Oxford University Press
- external identifiers
-
- wos:000077983000100
- scopus:0032895474
- ISSN
- 1362-4962
- DOI
- 10.1093/nar/27.1.362
- language
- English
- LU publication?
- no
- id
- 28b6cfd3-e0c2-4280-87c6-5339789cd376 (old id 3852360)
- date added to LUP
- 2016-04-01 11:34:29
- date last changed
- 2022-01-26 07:15:01
@article{28b6cfd3-e0c2-4280-87c6-5339789cd376,
abstract = {{KinMutBase (http://www.uta.fi/laitokset/imt/KinMutBase. html) is a registry of mutations in human protein kinases related to disorders. Kinases are essential cellular signalling molecules, in which mutations can lead into diseases including, e.g., immunodeficiencies, cancers and endocrine disorders. The first release of KinMutBase contains information for nine protein tyrosine kinases. There are altogether 170 entries representing 273 families and 403 patients. Mutations appear both in conserved hallmark residues of the kinases as well as in non-homologous sites. The KinMutBase WWW pages provide plenty of information, namely mutation statistics and display, clickable sequences with mutations, restriction enzyme patterns and online submission.}},
author = {{Stenberg, KAE and Riikonen, PT and Vihinen, Mauno}},
issn = {{1362-4962}},
language = {{eng}},
number = {{1}},
pages = {{362--364}},
publisher = {{Oxford University Press}},
series = {{Nucleic Acids Research}},
title = {{KinMutBase, a database of human disease-causing protein kinase mutations}},
url = {{http://dx.doi.org/10.1093/nar/27.1.362}},
doi = {{10.1093/nar/27.1.362}},
volume = {{27}},
year = {{1999}},
}