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No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

Kaspersen, M. D. ; Bungum, Mona LU ; Fedder, J. ; Bonde, J. ; Larsen, P. B. ; Ingerslev, H. J. and Hollsberg, P. (2013) In Andrology 1(3). p.361-364
Abstract
It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
human herpesvirus, human papillomavirus, Sperm Chromatin Structure, Assay, sperm DNA fragmentation
in
Andrology
volume
1
issue
3
pages
361 - 364
publisher
Wiley-Blackwell
external identifiers
  • wos:000317988900002
  • scopus:84885586668
  • pmid:23444031
ISSN
2047-2927
DOI
10.1111/j.2047-2927.2013.00067.x
language
English
LU publication?
yes
id
33584d68-c2b0-4ebf-b5a9-e678ceaaa9f7 (old id 3853587)
date added to LUP
2016-04-01 10:35:31
date last changed
2020-06-17 01:24:28
@article{33584d68-c2b0-4ebf-b5a9-e678ceaaa9f7,
  abstract     = {It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.},
  author       = {Kaspersen, M. D. and Bungum, Mona and Fedder, J. and Bonde, J. and Larsen, P. B. and Ingerslev, H. J. and Hollsberg, P.},
  issn         = {2047-2927},
  language     = {eng},
  number       = {3},
  pages        = {361--364},
  publisher    = {Wiley-Blackwell},
  series       = {Andrology},
  title        = {No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus},
  url          = {http://dx.doi.org/10.1111/j.2047-2927.2013.00067.x},
  doi          = {10.1111/j.2047-2927.2013.00067.x},
  volume       = {1},
  year         = {2013},
}