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How do Swedish paediatric clinics diagnose coeliac disease? Results of a nationwide questionnaire study

Stenhammar, Lars ; Hogberg, Lotta ; Danielsson, Lars LU ; Ascher, Henry ; Dannaeus, Anders ; Hernell, Olle ; Ivarsson, Anneli ; Lindberg, Eva ; Lindquist, Bo and Nivenius, Kerstin (2006) In Acta Pædiatrica 95(11). p.1495-1497
Abstract
Background and aim: Diagnosis of coeliac disease is based on the demonstration of enteropathy in a small bowel biopsy. Correct diagnosis is of utmost importance, since the need for dietary management is life long, and inadequate treatment may lead to potentially serious complications. The Swedish Working Group for Paediatric Coeliac Disease has published guidelines for the diagnosis of childhood coeliac disease. The present questionnaire was designed in order to create the basis for revision of those guidelines. Methods: In 2004, a nationwide questionnaire concerning current diagnostic routines was sent to all 45 paediatric clinics performing small bowel biopsy. All clinics responded. Results: All clinics base their diagnosis on small... (More)
Background and aim: Diagnosis of coeliac disease is based on the demonstration of enteropathy in a small bowel biopsy. Correct diagnosis is of utmost importance, since the need for dietary management is life long, and inadequate treatment may lead to potentially serious complications. The Swedish Working Group for Paediatric Coeliac Disease has published guidelines for the diagnosis of childhood coeliac disease. The present questionnaire was designed in order to create the basis for revision of those guidelines. Methods: In 2004, a nationwide questionnaire concerning current diagnostic routines was sent to all 45 paediatric clinics performing small bowel biopsy. All clinics responded. Results: All clinics base their diagnosis on small bowel biopsy findings at presentation. Furthermore, in 24 (53%) of the clinics, children with suspected coeliac disease are investigated by small bowel biopsy both at presentation and follow-up while on a gluten-free diet. Eighteen (40%) of the clinics employ a different diagnostic routine for children under 2 y of age than for those older than 2 y. All clinics use coeliac serological testing at various stages of the diagnostic procedure. Conclusion: All Swedish paediatric clinics perform a small bowel biopsy at presentation in children with suspected coeliac disease, and the majority of clinics perform a second biopsy when the child is on a gluten-free diet. Serological testing is frequently used as a diagnostic aid and in the monitoring of the disease while on a gluten-free diet. (Less)
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author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
small bowel biopsy, coeliac disease, serological tests
in
Acta Pædiatrica
volume
95
issue
11
pages
1495 - 1497
publisher
Wiley-Blackwell
external identifiers
  • wos:000241520400029
  • scopus:33750427219
ISSN
1651-2227
DOI
10.1080/08035250600636552
language
English
LU publication?
yes
id
5aba4734-0c21-4f53-a057-a46ea7a64b20 (old id 387173)
date added to LUP
2016-04-01 16:42:39
date last changed
2021-02-17 05:40:49
@article{5aba4734-0c21-4f53-a057-a46ea7a64b20,
  abstract     = {Background and aim: Diagnosis of coeliac disease is based on the demonstration of enteropathy in a small bowel biopsy. Correct diagnosis is of utmost importance, since the need for dietary management is life long, and inadequate treatment may lead to potentially serious complications. The Swedish Working Group for Paediatric Coeliac Disease has published guidelines for the diagnosis of childhood coeliac disease. The present questionnaire was designed in order to create the basis for revision of those guidelines. Methods: In 2004, a nationwide questionnaire concerning current diagnostic routines was sent to all 45 paediatric clinics performing small bowel biopsy. All clinics responded. Results: All clinics base their diagnosis on small bowel biopsy findings at presentation. Furthermore, in 24 (53%) of the clinics, children with suspected coeliac disease are investigated by small bowel biopsy both at presentation and follow-up while on a gluten-free diet. Eighteen (40%) of the clinics employ a different diagnostic routine for children under 2 y of age than for those older than 2 y. All clinics use coeliac serological testing at various stages of the diagnostic procedure. Conclusion: All Swedish paediatric clinics perform a small bowel biopsy at presentation in children with suspected coeliac disease, and the majority of clinics perform a second biopsy when the child is on a gluten-free diet. Serological testing is frequently used as a diagnostic aid and in the monitoring of the disease while on a gluten-free diet.},
  author       = {Stenhammar, Lars and Hogberg, Lotta and Danielsson, Lars and Ascher, Henry and Dannaeus, Anders and Hernell, Olle and Ivarsson, Anneli and Lindberg, Eva and Lindquist, Bo and Nivenius, Kerstin},
  issn         = {1651-2227},
  language     = {eng},
  number       = {11},
  pages        = {1495--1497},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Pædiatrica},
  title        = {How do Swedish paediatric clinics diagnose coeliac disease? Results of a nationwide questionnaire study},
  url          = {http://dx.doi.org/10.1080/08035250600636552},
  doi          = {10.1080/08035250600636552},
  volume       = {95},
  year         = {2006},
}