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Penile intraepithelial neoplasia: Results of photodynarnic therapy

Paoli, John ; Ternesten Bratel, Annika ; Lowhagen, Gun-Britt ; Stenquist, Bo ; Forslund, Ola LU and Wennberg, Ann-Marie (2006) In Acta Dermato-Venereologica 86(5). p.418-421
Abstract
Failure of response to treatment or recurrent disease is often noted in patients with penile intraepithelial neoplasia. Photodynamic therapy has recently been added to the list of treatment modalities used for this diagnosis. Our primary objective was to study the results of photodynamic therapy in the treatment of penile intraepithelial neoplasia in men over the age of 40 years. Ten patients aged 42-82 years with histopathologically confirmed lesions were studied. Lesions initially responded to photodynamic therapy in 7 out of 10 patients. Four of these patients presented no recurrences during a mean follow-up of 35 months, and were completely cleared after 2-8 treatments (mean 4.5 treatments). Three patients presented recurrences after... (More)
Failure of response to treatment or recurrent disease is often noted in patients with penile intraepithelial neoplasia. Photodynamic therapy has recently been added to the list of treatment modalities used for this diagnosis. Our primary objective was to study the results of photodynamic therapy in the treatment of penile intraepithelial neoplasia in men over the age of 40 years. Ten patients aged 42-82 years with histopathologically confirmed lesions were studied. Lesions initially responded to photodynamic therapy in 7 out of 10 patients. Four of these patients presented no recurrences during a mean follow-up of 35 months, and were completely cleared after 2-8 treatments (mean 4.5 treatments). Three patients presented recurrences after treatment. No patient developed invasive penile cancer (mean follow-up 46.5 months). Photodynamic therapy is an alternative in the treatment of penile intraepithelial neoplasia, although prospective randomized trials are required to provide therapeutic guidelines. (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
papilloma virus, human, erythroplasia of Queyrat, Bowen's disease, bowenoid papulosis, lichen sclerosus
in
Acta Dermato-Venereologica
volume
86
issue
5
pages
418 - 421
publisher
Medical Journals Limited
external identifiers
  • pmid:16955186
  • wos:000241130600007
  • scopus:33749009749
ISSN
1651-2057
DOI
10.2340/00015555-0130
language
English
LU publication?
yes
id
a0b19485-63d1-42a9-b52a-4b450d121cae (old id 388764)
date added to LUP
2016-04-01 16:38:11
date last changed
2020-09-30 04:07:43
@article{a0b19485-63d1-42a9-b52a-4b450d121cae,
  abstract     = {Failure of response to treatment or recurrent disease is often noted in patients with penile intraepithelial neoplasia. Photodynamic therapy has recently been added to the list of treatment modalities used for this diagnosis. Our primary objective was to study the results of photodynamic therapy in the treatment of penile intraepithelial neoplasia in men over the age of 40 years. Ten patients aged 42-82 years with histopathologically confirmed lesions were studied. Lesions initially responded to photodynamic therapy in 7 out of 10 patients. Four of these patients presented no recurrences during a mean follow-up of 35 months, and were completely cleared after 2-8 treatments (mean 4.5 treatments). Three patients presented recurrences after treatment. No patient developed invasive penile cancer (mean follow-up 46.5 months). Photodynamic therapy is an alternative in the treatment of penile intraepithelial neoplasia, although prospective randomized trials are required to provide therapeutic guidelines.},
  author       = {Paoli, John and Ternesten Bratel, Annika and Lowhagen, Gun-Britt and Stenquist, Bo and Forslund, Ola and Wennberg, Ann-Marie},
  issn         = {1651-2057},
  language     = {eng},
  number       = {5},
  pages        = {418--421},
  publisher    = {Medical Journals Limited},
  series       = {Acta Dermato-Venereologica},
  title        = {Penile intraepithelial neoplasia: Results of photodynarnic therapy},
  url          = {http://dx.doi.org/10.2340/00015555-0130},
  doi          = {10.2340/00015555-0130},
  volume       = {86},
  year         = {2006},
}