Preliminary study of D-dimer as a possible marker of acute bowel ischaemia
Acosta, Stefan LU
; Nilsson, T K
and Bjorck, M
(2001)
In British Journal of Surgery
88(3).
p.385-388
- Abstract
- BACKGROUND: Occlusion of the superior mesenteric artery (SMA) demands prompt recognition and diagnosis. No accurate diagnostic method is available. The aim of this study was to determine whether the fibrinolytic marker D-dimer is a useful early marker of acute bowel ischaemia. METHODS: Fourteen patients suspected of having acute bowel ischaemia were analysed for an increase in plasma D-dimer level. RESULTS: Six patients had embolic or thrombotic occlusion of the SMA and all had significantly higher D-dimer levels than those without thromboembolic occlusion (P < 0.05). Four patients with strangulation of the small bowel due to adhesions and one with a ruptured aortic aneurysm also had raised D-dimer values. CONCLUSION: In patients with... (More)
- BACKGROUND: Occlusion of the superior mesenteric artery (SMA) demands prompt recognition and diagnosis. No accurate diagnostic method is available. The aim of this study was to determine whether the fibrinolytic marker D-dimer is a useful early marker of acute bowel ischaemia. METHODS: Fourteen patients suspected of having acute bowel ischaemia were analysed for an increase in plasma D-dimer level. RESULTS: Six patients had embolic or thrombotic occlusion of the SMA and all had significantly higher D-dimer levels than those without thromboembolic occlusion (P < 0.05). Four patients with strangulation of the small bowel due to adhesions and one with a ruptured aortic aneurysm also had raised D-dimer values. CONCLUSION: In patients with suspected thromboembolic occlusive disease of the SMA, a raised level of D-dimer indicated the presence of acute bowel ischaemia, whatever the cause. A more extensive prospective study is needed to evaluate a potential survival benefit using the test as a marker of the need for urgent laparotomy. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1119746
- author
- Acosta, Stefan
LU
; Nilsson, T K
and Bjorck, M
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Surgery
- volume
- 88
- issue
- 3
- pages
- 385 - 388
- publisher
- Oxford University Press
- external identifiers
-
- pmid:11260104
- scopus:0035071918
- ISSN
- 1365-2168
- DOI
- 10.1046/j.1365-2168.2001.01711.x
- language
- English
- LU publication?
- no
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200)
- id
- 38aa22a3-a352-4484-a34e-2d2f110db95f (old id 1119746)
- date added to LUP
- 2016-04-01 12:08:06
- date last changed
- 2022-01-26 23:19:35
@article{38aa22a3-a352-4484-a34e-2d2f110db95f,
abstract = {{BACKGROUND: Occlusion of the superior mesenteric artery (SMA) demands prompt recognition and diagnosis. No accurate diagnostic method is available. The aim of this study was to determine whether the fibrinolytic marker D-dimer is a useful early marker of acute bowel ischaemia. METHODS: Fourteen patients suspected of having acute bowel ischaemia were analysed for an increase in plasma D-dimer level. RESULTS: Six patients had embolic or thrombotic occlusion of the SMA and all had significantly higher D-dimer levels than those without thromboembolic occlusion (P < 0.05). Four patients with strangulation of the small bowel due to adhesions and one with a ruptured aortic aneurysm also had raised D-dimer values. CONCLUSION: In patients with suspected thromboembolic occlusive disease of the SMA, a raised level of D-dimer indicated the presence of acute bowel ischaemia, whatever the cause. A more extensive prospective study is needed to evaluate a potential survival benefit using the test as a marker of the need for urgent laparotomy.}},
author = {{Acosta, Stefan and Nilsson, T K and Bjorck, M}},
issn = {{1365-2168}},
language = {{eng}},
number = {{3}},
pages = {{385--388}},
publisher = {{Oxford University Press}},
series = {{British Journal of Surgery}},
title = {{Preliminary study of D-dimer as a possible marker of acute bowel ischaemia}},
url = {{http://dx.doi.org/10.1046/j.1365-2168.2001.01711.x}},
doi = {{10.1046/j.1365-2168.2001.01711.x}},
volume = {{88}},
year = {{2001}},
}