Tyrosine-hydroxylase-containing neurons in the primate basal forebrain magnocellular complex
Gouras, Gunnar K. LU
; Rance, Naomi E.
; Scott Young, W.
and Koliatsos, Vassilis E.
(1992)
In Brain Research
584(1-2).
p.287-293
- Abstract
Immunocytochemistry and in situ hybridization for tyrosine hydroxylase (TH) were used to study the distribution of putative catecholaminergic neurons in the basal forebrain magnocellular complex (BFMC) of monkeys and humans. Magnocellular TH-expressing neurons in the primate BFMC are distributed along a rostrocaudal gradient, with the largest proportion of these cells located in the medial septal nucleus and nucleus of the diagonal band of Broca; smaller TH-containing neurons generally follow the same distribution. These findings suggest that, within rostromedial segments of the BFMC, there is a distinct subpopulation of neurons that express catecholamine-synthesizing enzymes. Further research is necessary to establish whether these... (More)
Immunocytochemistry and in situ hybridization for tyrosine hydroxylase (TH) were used to study the distribution of putative catecholaminergic neurons in the basal forebrain magnocellular complex (BFMC) of monkeys and humans. Magnocellular TH-expressing neurons in the primate BFMC are distributed along a rostrocaudal gradient, with the largest proportion of these cells located in the medial septal nucleus and nucleus of the diagonal band of Broca; smaller TH-containing neurons generally follow the same distribution. These findings suggest that, within rostromedial segments of the BFMC, there is a distinct subpopulation of neurons that express catecholamine-synthesizing enzymes. Further research is necessary to establish whether these neurons utilize one or more catecholamines as neurotransmitters.
(Less)
- author
- Gouras, Gunnar K.
LU
; Rance, Naomi E.
; Scott Young, W.
and Koliatsos, Vassilis E.
- publishing date
- 1992-07-03
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Catecholaminergic, Diagonal band, Human, Monkey, Nucleus basalis, Septum
- in
- Brain Research
- volume
- 584
- issue
- 1-2
- pages
- 287 - 293
- publisher
- Elsevier
- external identifiers
-
- scopus:0026684974
- pmid:1355392
- ISSN
- 0006-8993
- DOI
- 10.1016/0006-8993(92)90907-Q
- language
- English
- LU publication?
- no
- id
- 391e819e-a2be-4f7f-823c-0c79382ed570
- date added to LUP
- 2020-02-20 14:35:39
- date last changed
- 2024-01-02 06:09:17
@article{391e819e-a2be-4f7f-823c-0c79382ed570,
abstract = {{<p>Immunocytochemistry and in situ hybridization for tyrosine hydroxylase (TH) were used to study the distribution of putative catecholaminergic neurons in the basal forebrain magnocellular complex (BFMC) of monkeys and humans. Magnocellular TH-expressing neurons in the primate BFMC are distributed along a rostrocaudal gradient, with the largest proportion of these cells located in the medial septal nucleus and nucleus of the diagonal band of Broca; smaller TH-containing neurons generally follow the same distribution. These findings suggest that, within rostromedial segments of the BFMC, there is a distinct subpopulation of neurons that express catecholamine-synthesizing enzymes. Further research is necessary to establish whether these neurons utilize one or more catecholamines as neurotransmitters.</p>}},
author = {{Gouras, Gunnar K. and Rance, Naomi E. and Scott Young, W. and Koliatsos, Vassilis E.}},
issn = {{0006-8993}},
keywords = {{Catecholaminergic; Diagonal band; Human; Monkey; Nucleus basalis; Septum}},
language = {{eng}},
month = {{07}},
number = {{1-2}},
pages = {{287--293}},
publisher = {{Elsevier}},
series = {{Brain Research}},
title = {{Tyrosine-hydroxylase-containing neurons in the primate basal forebrain magnocellular complex}},
url = {{http://dx.doi.org/10.1016/0006-8993(92)90907-Q}},
doi = {{10.1016/0006-8993(92)90907-Q}},
volume = {{584}},
year = {{1992}},
}