Chemical characterization of cyanogen bromide fragments from the beta-chain of human complement factor C3
(1984) In FEBS Letters 169(1). p.57-62- Abstract
- The isolated beta-chain of human complement factor C3 (C3 beta) was fragmented by cyanogen bromide. Nine fragments were defined by gel filtration and high-pressure liquid chromatography, and characterized with respect to their Mr, amino acid composition and N-terminal amino acid sequence. Approx. 30% of the primary structure of C3 beta was determined. Alignment of the 3 N-terminal fragments allowed determination of 61 of the amino terminal residues of C3 beta. This region demonstrated 40% homology with the sequence in the N-terminal segment of the alpha-chain of the cobra venom factor.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3965056
- author
- Lundwall, Åke LU ; Hellman, U. ; Eggertsen, G. and Sjöquist, J.
- publishing date
- 1984
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- *Cyanogen Bromide, Complement C3/*analysis, High Pressure Liquid, Gel, Chromatography, Amino Acid Sequence, Amino Acids/analysis, Humans, Peptide Fragments/*analysis, Research Support, Non-U.S. Gov't
- in
- FEBS Letters
- volume
- 169
- issue
- 1
- pages
- 57 - 62
- publisher
- Wiley-Blackwell
- ISSN
- 1873-3468
- language
- English
- LU publication?
- no
- additional info
- 1
- id
- 90cc740a-84d1-4434-9e04-4a140bfa42b7 (old id 3965056)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6714418
- date added to LUP
- 2016-04-04 14:21:53
- date last changed
- 2020-05-20 08:53:15
@article{90cc740a-84d1-4434-9e04-4a140bfa42b7, abstract = {{The isolated beta-chain of human complement factor C3 (C3 beta) was fragmented by cyanogen bromide. Nine fragments were defined by gel filtration and high-pressure liquid chromatography, and characterized with respect to their Mr, amino acid composition and N-terminal amino acid sequence. Approx. 30% of the primary structure of C3 beta was determined. Alignment of the 3 N-terminal fragments allowed determination of 61 of the amino terminal residues of C3 beta. This region demonstrated 40% homology with the sequence in the N-terminal segment of the alpha-chain of the cobra venom factor.}}, author = {{Lundwall, Åke and Hellman, U. and Eggertsen, G. and Sjöquist, J.}}, issn = {{1873-3468}}, keywords = {{*Cyanogen Bromide; Complement C3/*analysis; High Pressure Liquid; Gel; Chromatography; Amino Acid Sequence; Amino Acids/analysis; Humans; Peptide Fragments/*analysis; Research Support; Non-U.S. Gov't}}, language = {{eng}}, number = {{1}}, pages = {{57--62}}, publisher = {{Wiley-Blackwell}}, series = {{FEBS Letters}}, title = {{Chemical characterization of cyanogen bromide fragments from the beta-chain of human complement factor C3}}, url = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6714418}}, volume = {{169}}, year = {{1984}}, }