Dynamic Guiding of Motor-Driven Microtubules on Electrically Heated, Smart Polymer Tracks
(2013) In Nano Letters 13(7). p.3434-3438- Abstract
- Biomolecular motor systems are attractive for future nanotechnological devices because they can replace nanofluidics by directed transport. However, the lack of methods to externally control motor-driven transport along complex paths limits their range of applications. Based on a thermo-responsive polymer, we developed a novel technique to guide microtubules propelled by kinesin-1 motors on a planar surface. Using electrically heated gold microstructures, the polymers were locally collapsed, creating dynamically switchable tracks that successfully guided microtubule movement.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3974081
- author
- Schroeder, Viktor ; Korten, Till ; Linke, Heiner ; Diez, Stefan and Maximov, Ivan LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Microtubule, kinesin, poly(N-isopropylacrylamide) (PNIPAM), directional, guiding, Y-junction
- in
- Nano Letters
- volume
- 13
- issue
- 7
- pages
- 3434 - 3438
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000321884300070
- scopus:84880156150
- pmid:23750886
- ISSN
- 1530-6992
- DOI
- 10.1021/nl402004s
- language
- English
- LU publication?
- yes
- id
- 9f1379ef-90d1-430a-b153-7e10d4fd4a9c (old id 3974081)
- date added to LUP
- 2016-04-01 13:05:37
- date last changed
- 2023-10-14 21:54:17
@article{9f1379ef-90d1-430a-b153-7e10d4fd4a9c, abstract = {{Biomolecular motor systems are attractive for future nanotechnological devices because they can replace nanofluidics by directed transport. However, the lack of methods to externally control motor-driven transport along complex paths limits their range of applications. Based on a thermo-responsive polymer, we developed a novel technique to guide microtubules propelled by kinesin-1 motors on a planar surface. Using electrically heated gold microstructures, the polymers were locally collapsed, creating dynamically switchable tracks that successfully guided microtubule movement.}}, author = {{Schroeder, Viktor and Korten, Till and Linke, Heiner and Diez, Stefan and Maximov, Ivan}}, issn = {{1530-6992}}, keywords = {{Microtubule; kinesin; poly(N-isopropylacrylamide) (PNIPAM); directional; guiding; Y-junction}}, language = {{eng}}, number = {{7}}, pages = {{3434--3438}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Nano Letters}}, title = {{Dynamic Guiding of Motor-Driven Microtubules on Electrically Heated, Smart Polymer Tracks}}, url = {{http://dx.doi.org/10.1021/nl402004s}}, doi = {{10.1021/nl402004s}}, volume = {{13}}, year = {{2013}}, }