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Changes in f-wave characteristics during cryoballoon catheter ablation

Henriksson, Mikael LU ; García-Alberola, Arcadi; Goya, Rebeca; Vadillo, Alba; Melgarejo-Meseguer, Francisco Manuel; Sandberg, Frida LU and Sörnmo, Leif LU (2018) In Physiological Measurement 39(10).
Abstract

OBJECTIVE: Changes in ECG-derived parameters are studied in atrial fibrillation (AF) patients undergoing cryoballoon catheter ablation.

APPROACH: Parameters characterizing f-wave frequency, morphology by phase dispersion, and amplitude are estimated using a model-based statistical approach. These parameters are studied before, during, and after ablation, as well as for AF type (paroxysmal/persistent). Seventy-seven (49/28 paroxysmal/persistent) AF patients undergoing de novo catheter ablation are included in the study, out of which 31 (16/15 paroxysmal/persistent) were in AF during the whole procedure. A signal quality index (SQI) is used to identify analyzable segments.

MAIN RESULTS: f-wave frequency decreased significantly... (More)

OBJECTIVE: Changes in ECG-derived parameters are studied in atrial fibrillation (AF) patients undergoing cryoballoon catheter ablation.

APPROACH: Parameters characterizing f-wave frequency, morphology by phase dispersion, and amplitude are estimated using a model-based statistical approach. These parameters are studied before, during, and after ablation, as well as for AF type (paroxysmal/persistent). Seventy-seven (49/28 paroxysmal/persistent) AF patients undergoing de novo catheter ablation are included in the study, out of which 31 (16/15 paroxysmal/persistent) were in AF during the whole procedure. A signal quality index (SQI) is used to identify analyzable segments.

MAIN RESULTS: f-wave frequency decreased significantly during ablation (p  =  0.001), in particular after ablation of the inferior right pulmonary vein (p  <  0.05). Frequency and phase dispersion differed significantly between paroxysmal and persistent AF (p  =  0.001 and p  <  0.05, respectively).

SIGNIFICANCE: This study demonstrates that a decrease in f-wave frequency can be distinguished during catheter ablation. The use of an SQI ensures reliable analysis and produces results significantly different from those obtained without an SQI.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physiological Measurement
volume
39
issue
10
pages
1 pages
publisher
IOP Publishing
external identifiers
  • scopus:85054442797
ISSN
0967-3334
DOI
10.1088/1361-6579/aadf1d
language
English
LU publication?
yes
id
3a5903f2-7769-4be9-97e9-fe43848309e0
date added to LUP
2018-10-31 12:14:21
date last changed
2018-10-31 12:14:21
@article{3a5903f2-7769-4be9-97e9-fe43848309e0,
  abstract     = {<p>OBJECTIVE: Changes in ECG-derived parameters are studied in atrial fibrillation (AF) patients undergoing cryoballoon catheter ablation.</p><p>APPROACH: Parameters characterizing f-wave frequency, morphology by phase dispersion, and amplitude are estimated using a model-based statistical approach. These parameters are studied before, during, and after ablation, as well as for AF type (paroxysmal/persistent). Seventy-seven (49/28 paroxysmal/persistent) AF patients undergoing de novo catheter ablation are included in the study, out of which 31 (16/15 paroxysmal/persistent) were in AF during the whole procedure. A signal quality index (SQI) is used to identify analyzable segments.</p><p>MAIN RESULTS: f-wave frequency decreased significantly during ablation (p  =  0.001), in particular after ablation of the inferior right pulmonary vein (p  &lt;  0.05). Frequency and phase dispersion differed significantly between paroxysmal and persistent AF (p  =  0.001 and p  &lt;  0.05, respectively).</p><p>SIGNIFICANCE: This study demonstrates that a decrease in f-wave frequency can be distinguished during catheter ablation. The use of an SQI ensures reliable analysis and produces results significantly different from those obtained without an SQI.</p>},
  author       = {Henriksson, Mikael and García-Alberola, Arcadi and Goya, Rebeca and Vadillo, Alba and Melgarejo-Meseguer, Francisco Manuel and Sandberg, Frida and Sörnmo, Leif},
  issn         = {0967-3334},
  language     = {eng},
  month        = {10},
  number       = {10},
  pages        = {1},
  publisher    = {IOP Publishing},
  series       = {Physiological Measurement},
  title        = {Changes in f-wave characteristics during cryoballoon catheter ablation},
  url          = {http://dx.doi.org/10.1088/1361-6579/aadf1d},
  volume       = {39},
  year         = {2018},
}