Insulin and glucagon release from the isolated pancreas of foetal and newborn mice
Lernmark, A. LU
and Wenngren, B. I.
(1972)
In Journal of Embryology and Experimental Morphology
28(3).
p.607-614
- Abstract
- The simultaneous release of insulin and glucagon was studied with isolated pancreas preparations from foetal and newborn mice. Glucose, alone or in combination with arginine, did not affect immunoreactive insulin (IRI) of glucagon-like immunoreactivity (GLI) release from the pancreases of 18-day-old foetal mice. However, on the first postnatal day, glucose stimulated the release of IRI and, in the presence of arginine, depressed that of GLI. It is concluded that the systems for recognition of glucose in mouse pancreatic α2-cells as well as those in the β-cells do not mature until after birth.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3a9ee31c-a67e-468a-845f-e3da7f247702
- author
- Lernmark, A.
LU
and Wenngren, B. I.
- publishing date
- 1972-12-01
- type
- Contribution to journal
- publication status
- published
- in
- Journal of Embryology and Experimental Morphology
- volume
- 28
- issue
- 3
- pages
- 607 - 614
- publisher
- The Company of Biologists Ltd
- external identifiers
-
- scopus:0015451559
- pmid:4655321
- ISSN
- 0022-0752
- language
- English
- LU publication?
- no
- id
- 3a9ee31c-a67e-468a-845f-e3da7f247702
- alternative location
- https://dev.biologists.org/content/28/3/607
- date added to LUP
- 2019-09-18 12:23:06
- date last changed
- 2024-03-13 08:26:44
@article{3a9ee31c-a67e-468a-845f-e3da7f247702,
abstract = {{The simultaneous release of insulin and glucagon was studied with isolated pancreas preparations from foetal and newborn mice. Glucose, alone or in combination with arginine, did not affect immunoreactive insulin (IRI) of glucagon-like immunoreactivity (GLI) release from the pancreases of 18-day-old foetal mice. However, on the first postnatal day, glucose stimulated the release of IRI and, in the presence of arginine, depressed that of GLI. It is concluded that the systems for recognition of glucose in mouse pancreatic α2-cells as well as those in the β-cells do not mature until after birth.}},
author = {{Lernmark, A. and Wenngren, B. I.}},
issn = {{0022-0752}},
language = {{eng}},
month = {{12}},
number = {{3}},
pages = {{607--614}},
publisher = {{The Company of Biologists Ltd}},
series = {{Journal of Embryology and Experimental Morphology}},
title = {{Insulin and glucagon release from the isolated pancreas of foetal and newborn mice}},
url = {{https://dev.biologists.org/content/28/3/607}},
volume = {{28}},
year = {{1972}},
}