Impact of socioeconomic factors and antibiotic prescribing on penicillin- non-susceptible Streptococcus pneumoniae in the city of Malmö.
(2005) In Scandinavian Journal of Infectious Diseases 37(6). p.436-441- Abstract
- Carriage or infection with penicillin-non-susceptible Streptococcus pneumoniae (PNSP) has been associated with antibiotic prescribing, socioeconomic factors, and attendance at day-care centres (DCCs). In the present study, linear regression was used to estimate the relation between these risk factors and the incidence of PNSP cases (non-susceptible defined as MIC >= 0.5 mu g/ml for penicillin) in 19 residential areas in Malmo. The number of PNSP cases was associated with the number of preschool children in the area (r=0.950, p<0.0001). The incidence of PNSP cases per 1000 children was positively correlated with antibiotic prescribing (r=0.614, p<0.01) but not with DCC attendance or any of the socioeconomic factors studied.... (More)
- Carriage or infection with penicillin-non-susceptible Streptococcus pneumoniae (PNSP) has been associated with antibiotic prescribing, socioeconomic factors, and attendance at day-care centres (DCCs). In the present study, linear regression was used to estimate the relation between these risk factors and the incidence of PNSP cases (non-susceptible defined as MIC >= 0.5 mu g/ml for penicillin) in 19 residential areas in Malmo. The number of PNSP cases was associated with the number of preschool children in the area (r=0.950, p<0.0001). The incidence of PNSP cases per 1000 children was positively correlated with antibiotic prescribing (r=0.614, p<0.01) but not with DCC attendance or any of the socioeconomic factors studied. Antibiotic prescribing was, however, positively correlated with per capita income (r=0.597, p<0.05). Thus, even if higher socioeconomic status alone had no apparent influence on the incidence of PNSP in Malmo, there was still an indirect relation between these 2 factors, since inhabitants in these areas consumed more antibiotics. Based on these results, the spread of antibiotic-resistant pneumococci seems to be most reliably restricted by pursuing a restrictive policy regarding antibiotic prescription. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/142179
- author
- Nilsson Wimar, Percy LU and Laurell, Martin LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Infectious Diseases
- volume
- 37
- issue
- 6
- pages
- 436 - 441
- publisher
- Informa Healthcare
- external identifiers
-
- wos:000230505200005
- pmid:16012003
- scopus:22844432336
- ISSN
- 1651-1980
- DOI
- 10.1080/00365540510037795
- language
- English
- LU publication?
- yes
- id
- 3ac0be75-cb03-4da9-8616-db1a02d9c81f (old id 142179)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16012003&dopt=Abstract
- date added to LUP
- 2016-04-01 16:46:00
- date last changed
- 2022-01-28 22:01:19
@article{3ac0be75-cb03-4da9-8616-db1a02d9c81f, abstract = {{Carriage or infection with penicillin-non-susceptible Streptococcus pneumoniae (PNSP) has been associated with antibiotic prescribing, socioeconomic factors, and attendance at day-care centres (DCCs). In the present study, linear regression was used to estimate the relation between these risk factors and the incidence of PNSP cases (non-susceptible defined as MIC >= 0.5 mu g/ml for penicillin) in 19 residential areas in Malmo. The number of PNSP cases was associated with the number of preschool children in the area (r=0.950, p<0.0001). The incidence of PNSP cases per 1000 children was positively correlated with antibiotic prescribing (r=0.614, p<0.01) but not with DCC attendance or any of the socioeconomic factors studied. Antibiotic prescribing was, however, positively correlated with per capita income (r=0.597, p<0.05). Thus, even if higher socioeconomic status alone had no apparent influence on the incidence of PNSP in Malmo, there was still an indirect relation between these 2 factors, since inhabitants in these areas consumed more antibiotics. Based on these results, the spread of antibiotic-resistant pneumococci seems to be most reliably restricted by pursuing a restrictive policy regarding antibiotic prescription.}}, author = {{Nilsson Wimar, Percy and Laurell, Martin}}, issn = {{1651-1980}}, language = {{eng}}, number = {{6}}, pages = {{436--441}}, publisher = {{Informa Healthcare}}, series = {{Scandinavian Journal of Infectious Diseases}}, title = {{Impact of socioeconomic factors and antibiotic prescribing on penicillin- non-susceptible Streptococcus pneumoniae in the city of Malmö.}}, url = {{http://dx.doi.org/10.1080/00365540510037795}}, doi = {{10.1080/00365540510037795}}, volume = {{37}}, year = {{2005}}, }