Evidence of Lipid Exchange in Styrene Maleic Acid Lipid Particle (SMALP) Nanodisc Systems
(2016) In Langmuir 32(45). p.11845-11853- Abstract
Styrene-alt-maleic acid lipid particles (SMALPs) are self-assembled discoidal structures composed of a polymer belt and a segment of lipid bilayer, which are capable of encapsulating membrane proteins directly from the cell membrane. Here we present evidence of the exchange of lipids between such "nanodiscs" and lipid monolayers adsorbed at either solid-liquid or air-liquid interfaces. This behavior has important implications for the potential uses of nanodiscs.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3b3c63a1-50df-495e-97d0-f9488d4b1387
- author
- Hazell, Gavin
; Arnold, Thomas
; Barker, Robert D.
; Clifton, Luke A.
; Steinke, Nina Juliane
; Tognoloni, Cecilia
and Edler, Karen J.
LU
- publishing date
- 2016-11-15
- type
- Contribution to journal
- publication status
- published
- in
- Langmuir
- volume
- 32
- issue
- 45
- pages
- 9 pages
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- scopus:84995790200
- ISSN
- 0743-7463
- DOI
- 10.1021/acs.langmuir.6b02927
- language
- English
- LU publication?
- no
- additional info
- Publisher Copyright: © 2016 American Chemical Society.
- id
- 3b3c63a1-50df-495e-97d0-f9488d4b1387
- date added to LUP
- 2023-01-18 09:17:14
- date last changed
- 2023-02-17 10:30:25
@article{3b3c63a1-50df-495e-97d0-f9488d4b1387, abstract = {{<p>Styrene-alt-maleic acid lipid particles (SMALPs) are self-assembled discoidal structures composed of a polymer belt and a segment of lipid bilayer, which are capable of encapsulating membrane proteins directly from the cell membrane. Here we present evidence of the exchange of lipids between such "nanodiscs" and lipid monolayers adsorbed at either solid-liquid or air-liquid interfaces. This behavior has important implications for the potential uses of nanodiscs.</p>}}, author = {{Hazell, Gavin and Arnold, Thomas and Barker, Robert D. and Clifton, Luke A. and Steinke, Nina Juliane and Tognoloni, Cecilia and Edler, Karen J.}}, issn = {{0743-7463}}, language = {{eng}}, month = {{11}}, number = {{45}}, pages = {{11845--11853}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Langmuir}}, title = {{Evidence of Lipid Exchange in Styrene Maleic Acid Lipid Particle (SMALP) Nanodisc Systems}}, url = {{http://dx.doi.org/10.1021/acs.langmuir.6b02927}}, doi = {{10.1021/acs.langmuir.6b02927}}, volume = {{32}}, year = {{2016}}, }