Receptor binding mimetics: a novel molecularly imprinted polymer
(1995) In Tetrahedron Letters 36(20). p.3563-3566- Abstract
- A novel molecularly imprinted polymer was prepared by copolymerization of trimethylolpropane trimethacrylate (1) and methacrylic acid (3) in the presence of a dipeptide acting as the template. The recognition capability of the synthetic receptor-like binding sites produced in the polymer network for the peptide was demonstrated by using the polymer as a chiral stationary phase in HPLC. The polymer was superior to previously reported molecularly imprinted polymers in that unusually high racemic resolution and load capacity were demonstrated.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1516080
- author
- Kempe, Maria LU and Mosbach, Klaus LU
- organization
- publishing date
- 1995
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Tetrahedron Letters
- volume
- 36
- issue
- 20
- pages
- 3563 - 3566
- publisher
- Elsevier
- external identifiers
-
- scopus:0029024451
- ISSN
- 0040-4039
- DOI
- 10.1016/0040-4039(95)00559-U
- language
- English
- LU publication?
- yes
- id
- 3b6fd1b7-a7ea-48bf-86a3-bff0008fe1a1 (old id 1516080)
- date added to LUP
- 2016-04-01 15:31:32
- date last changed
- 2021-01-03 03:41:58
@article{3b6fd1b7-a7ea-48bf-86a3-bff0008fe1a1, abstract = {{A novel molecularly imprinted polymer was prepared by copolymerization of trimethylolpropane trimethacrylate (1) and methacrylic acid (3) in the presence of a dipeptide acting as the template. The recognition capability of the synthetic receptor-like binding sites produced in the polymer network for the peptide was demonstrated by using the polymer as a chiral stationary phase in HPLC. The polymer was superior to previously reported molecularly imprinted polymers in that unusually high racemic resolution and load capacity were demonstrated.}}, author = {{Kempe, Maria and Mosbach, Klaus}}, issn = {{0040-4039}}, language = {{eng}}, number = {{20}}, pages = {{3563--3566}}, publisher = {{Elsevier}}, series = {{Tetrahedron Letters}}, title = {{Receptor binding mimetics: a novel molecularly imprinted polymer}}, url = {{http://dx.doi.org/10.1016/0040-4039(95)00559-U}}, doi = {{10.1016/0040-4039(95)00559-U}}, volume = {{36}}, year = {{1995}}, }