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Depression in People With Dementia and Caregiver Outcomes : Results From the European Right Time Place Care Study

Parrotta, Ilaria ; De Mauleon, Adelaide ; Abdeljalil, Anne Bahia ; De Souto Barreto, Philipe ; Lethin, Connie LU orcid ; Veerbek, Hilde ; Stephan, Astrid ; Saks, Kay ; Zabalegui, Adelaida and Soto Martin, Maria Eugenia (2020) In Journal of the American Medical Directors Association 21(6). p.872-878
Abstract

Objective: To investigate the cross-sectional associations between depression in people with dementia and both caregiver burden and quality of life in 8 European countries, and to test these associations compared with the presence of other neuropsychiatric symptoms. Design: Cross-sectional study. Setting and Participants: In total, 1223 dyads comprised of informal caregivers and people with dementia living in a community-dwelling setting, recruited from the Right Time Place Care study, a cohort survey from 8 European countries. Measures: To test the associations between depression (according to the Cornell Scale for Depression in Dementia) and informal caregiver burden (defined by the Zarit scale and hours of supervision in terms of... (More)

Objective: To investigate the cross-sectional associations between depression in people with dementia and both caregiver burden and quality of life in 8 European countries, and to test these associations compared with the presence of other neuropsychiatric symptoms. Design: Cross-sectional study. Setting and Participants: In total, 1223 dyads comprised of informal caregivers and people with dementia living in a community-dwelling setting, recruited from the Right Time Place Care study, a cohort survey from 8 European countries. Measures: To test the associations between depression (according to the Cornell Scale for Depression in Dementia) and informal caregiver burden (defined by the Zarit scale and hours of supervision in terms of Resource Utilization in Dementia), distress (defined by the Neuropsychiatric Inventory Questionnaire distress score), and quality of life (according to the visual analogue scale and 12-item General Health Questionnaire). Results: Linear regressions showed an association between depression and main outcomes (Zarit scale: β 3.7; P = .001; hours of supervision: β 1.7; P = .004; Neuropsychiatric Inventory Questionnaire distress score: β 1.2; P = .002). A similar association was found concerning psychological and overall well-being (12-item General Health Questionnaire: β 1.8; P < .001; Euroqol Visual Analogue Scale: β −4.1; P = .003). Both associations remained significant despite the presence of other NPS and after adjusting for confounders. Conclusions and Implications: Further studies are needed to assess whether providing tailored strategies for optimizing diagnosis and managing of depression in people with dementia might improve caregiver quality of life and reduce their burden in the community-dwelling setting.

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author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
burden, caregiver, dementia, Depression, elderly
in
Journal of the American Medical Directors Association
volume
21
issue
6
pages
7 pages
publisher
Elsevier
external identifiers
  • pmid:32307275
  • scopus:85083315693
ISSN
1525-8610
DOI
10.1016/j.jamda.2020.02.023
language
English
LU publication?
yes
id
3cb36485-c6d8-491a-b990-51ed8427f9da
date added to LUP
2020-05-08 16:51:06
date last changed
2024-06-26 15:16:38
@article{3cb36485-c6d8-491a-b990-51ed8427f9da,
  abstract     = {{<p>Objective: To investigate the cross-sectional associations between depression in people with dementia and both caregiver burden and quality of life in 8 European countries, and to test these associations compared with the presence of other neuropsychiatric symptoms. Design: Cross-sectional study. Setting and Participants: In total, 1223 dyads comprised of informal caregivers and people with dementia living in a community-dwelling setting, recruited from the Right Time Place Care study, a cohort survey from 8 European countries. Measures: To test the associations between depression (according to the Cornell Scale for Depression in Dementia) and informal caregiver burden (defined by the Zarit scale and hours of supervision in terms of Resource Utilization in Dementia), distress (defined by the Neuropsychiatric Inventory Questionnaire distress score), and quality of life (according to the visual analogue scale and 12-item General Health Questionnaire). Results: Linear regressions showed an association between depression and main outcomes (Zarit scale: β 3.7; P = .001; hours of supervision: β 1.7; P = .004; Neuropsychiatric Inventory Questionnaire distress score: β 1.2; P = .002). A similar association was found concerning psychological and overall well-being (12-item General Health Questionnaire: β 1.8; P &lt; .001; Euroqol Visual Analogue Scale: β −4.1; P = .003). Both associations remained significant despite the presence of other NPS and after adjusting for confounders. Conclusions and Implications: Further studies are needed to assess whether providing tailored strategies for optimizing diagnosis and managing of depression in people with dementia might improve caregiver quality of life and reduce their burden in the community-dwelling setting.</p>}},
  author       = {{Parrotta, Ilaria and De Mauleon, Adelaide and Abdeljalil, Anne Bahia and De Souto Barreto, Philipe and Lethin, Connie and Veerbek, Hilde and Stephan, Astrid and Saks, Kay and Zabalegui, Adelaida and Soto Martin, Maria Eugenia}},
  issn         = {{1525-8610}},
  keywords     = {{burden; caregiver; dementia; Depression; elderly}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{6}},
  pages        = {{872--878}},
  publisher    = {{Elsevier}},
  series       = {{Journal of the American Medical Directors Association}},
  title        = {{Depression in People With Dementia and Caregiver Outcomes : Results From the European Right Time Place Care Study}},
  url          = {{http://dx.doi.org/10.1016/j.jamda.2020.02.023}},
  doi          = {{10.1016/j.jamda.2020.02.023}},
  volume       = {{21}},
  year         = {{2020}},
}