Evaluation of the generality and accuracy of a new mesh morphing procedure for the human femur.
Grassi, Lorenzo LU
; Hraiech, Najah
; Schileo, Enrico
; Ansaloni, Mauro
; Rochette, Michel
and Viceconti, Marco
(2011)
In Medical Engineering & Physics
33(1).
p.112-120
- Abstract
- Various papers described mesh morphing techniques for computational biomechanics, but none of them provided a quantitative assessment of generality, robustness, automation, and accuracy in predicting strains. This study aims to quantitatively evaluate the performance of a novel mesh-morphing algorithm. A mesh-morphing algorithm based on radial-basis functions and on manual selection of corresponding landmarks on template and target was developed. The periosteal geometries of 100 femurs were derived from a computed tomography scan database and used to test the algorithm generality in producing finite element (FE) morphed meshes. A published benchmark, consisting of eight femurs for which in vitro strain measurements and standard FE model... (More)
- Various papers described mesh morphing techniques for computational biomechanics, but none of them provided a quantitative assessment of generality, robustness, automation, and accuracy in predicting strains. This study aims to quantitatively evaluate the performance of a novel mesh-morphing algorithm. A mesh-morphing algorithm based on radial-basis functions and on manual selection of corresponding landmarks on template and target was developed. The periosteal geometries of 100 femurs were derived from a computed tomography scan database and used to test the algorithm generality in producing finite element (FE) morphed meshes. A published benchmark, consisting of eight femurs for which in vitro strain measurements and standard FE model strain prediction accuracy were available, was used to assess the accuracy of morphed FE models in predicting strains. Relevant parameters were identified to test the algorithm robustness to operative conditions. Time and effort needed were evaluated to define the algorithm degree of automation. Morphing was successful for 95% of the specimens, with mesh quality indicators comparable to those of standard FE meshes. Accuracy of the morphed meshes in predicting strains was good (R(2)>0.9, RMSE%<10%) and not statistically different from the standard meshes (p-value=0.1083). The algorithm was robust to inter- and intra-operator variability, target geometry refinement (p-value>0.05) and partially to the number of landmark used. Producing a morphed mesh starting from the triangularized geometry of the specimen requires on average 10 min. The proposed method is general, robust, automated, and accurate enough to be used in bone FE modelling from diagnostic data, and prospectively in applications such as statistical shape modelling. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2298284
- author
- Grassi, Lorenzo
LU
; Hraiech, Najah
; Schileo, Enrico
; Ansaloni, Mauro
; Rochette, Michel
and Viceconti, Marco
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bone biomechanics, Femur, Subject-specific finite element model, Mesh morphing, Radial basis function
- in
- Medical Engineering & Physics
- volume
- 33
- issue
- 1
- pages
- 112 - 120
- publisher
- Elsevier
- external identifiers
-
- scopus:78650938491
- ISSN
- 1873-4030
- language
- English
- LU publication?
- no
- id
- 3cf56751-4529-499f-b393-8621e3fe690b (old id 2298284)
- alternative location
- http://www.sciencedirect.com/science/article/pii/S1350453310002109
- date added to LUP
- 2016-04-04 11:07:31
- date last changed
- 2022-04-24 00:08:49
@article{3cf56751-4529-499f-b393-8621e3fe690b,
abstract = {{Various papers described mesh morphing techniques for computational biomechanics, but none of them provided a quantitative assessment of generality, robustness, automation, and accuracy in predicting strains. This study aims to quantitatively evaluate the performance of a novel mesh-morphing algorithm. A mesh-morphing algorithm based on radial-basis functions and on manual selection of corresponding landmarks on template and target was developed. The periosteal geometries of 100 femurs were derived from a computed tomography scan database and used to test the algorithm generality in producing finite element (FE) morphed meshes. A published benchmark, consisting of eight femurs for which in vitro strain measurements and standard FE model strain prediction accuracy were available, was used to assess the accuracy of morphed FE models in predicting strains. Relevant parameters were identified to test the algorithm robustness to operative conditions. Time and effort needed were evaluated to define the algorithm degree of automation. Morphing was successful for 95% of the specimens, with mesh quality indicators comparable to those of standard FE meshes. Accuracy of the morphed meshes in predicting strains was good (R(2)>0.9, RMSE%<10%) and not statistically different from the standard meshes (p-value=0.1083). The algorithm was robust to inter- and intra-operator variability, target geometry refinement (p-value>0.05) and partially to the number of landmark used. Producing a morphed mesh starting from the triangularized geometry of the specimen requires on average 10 min. The proposed method is general, robust, automated, and accurate enough to be used in bone FE modelling from diagnostic data, and prospectively in applications such as statistical shape modelling.}},
author = {{Grassi, Lorenzo and Hraiech, Najah and Schileo, Enrico and Ansaloni, Mauro and Rochette, Michel and Viceconti, Marco}},
issn = {{1873-4030}},
keywords = {{Bone biomechanics; Femur; Subject-specific finite element model; Mesh morphing; Radial basis function}},
language = {{eng}},
number = {{1}},
pages = {{112--120}},
publisher = {{Elsevier}},
series = {{Medical Engineering & Physics}},
title = {{Evaluation of the generality and accuracy of a new mesh morphing procedure for the human femur.}},
url = {{http://www.sciencedirect.com/science/article/pii/S1350453310002109}},
volume = {{33}},
year = {{2011}},
}