Simple model for the growth behaviour of mixed lecithin-bile salt micelles
(2011) In Physical Chemistry Chemical Physics 13(8). p.3171-3178- Abstract
- Mixed lecithin-bile salt micelles are known to have a cylindrical or worm-like structure. We investigated their shape, length, flexibility and cross-sectional structure using small-angle neutron scattering (SANS). A broad range of sample compositions was studied varying both the total amphiphile concentration and the molar ratio of bile salt (sodium taurochenodeoxycholate, NaTCDC) to lecithin (egg yolk phosphatidylcholine, EYL). The length of the micelles was quantitatively linked to the micellar composition by introducing a simple model. The model takes into account the partitioning of lecithin and bile salt between the bulk, cylindrical parts and the end caps of the micelles. The model also sheds light on the organization of the... (More)
- Mixed lecithin-bile salt micelles are known to have a cylindrical or worm-like structure. We investigated their shape, length, flexibility and cross-sectional structure using small-angle neutron scattering (SANS). A broad range of sample compositions was studied varying both the total amphiphile concentration and the molar ratio of bile salt (sodium taurochenodeoxycholate, NaTCDC) to lecithin (egg yolk phosphatidylcholine, EYL). The length of the micelles was quantitatively linked to the micellar composition by introducing a simple model. The model takes into account the partitioning of lecithin and bile salt between the bulk, cylindrical parts and the end caps of the micelles. The model also sheds light on the organization of the micelles, both in their cylindrical regions and end caps. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1872531
- author
- Madenci, Dilek ; Salonen, Anniina ; Schurtenberger, Peter LU ; Pedersen, Jan Skov and Egelhaaf, Stefan U.
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Physical Chemistry Chemical Physics
- volume
- 13
- issue
- 8
- pages
- 3171 - 3178
- publisher
- Royal Society of Chemistry
- external identifiers
-
- wos:000287041700020
- scopus:79951497644
- pmid:21135948
- ISSN
- 1463-9084
- DOI
- 10.1039/c0cp01700k
- language
- English
- LU publication?
- yes
- id
- 3d0f9c23-d900-4e9a-97b8-fe184f2ee4c7 (old id 1872531)
- date added to LUP
- 2016-04-01 14:29:27
- date last changed
- 2022-01-28 00:51:53
@article{3d0f9c23-d900-4e9a-97b8-fe184f2ee4c7, abstract = {{Mixed lecithin-bile salt micelles are known to have a cylindrical or worm-like structure. We investigated their shape, length, flexibility and cross-sectional structure using small-angle neutron scattering (SANS). A broad range of sample compositions was studied varying both the total amphiphile concentration and the molar ratio of bile salt (sodium taurochenodeoxycholate, NaTCDC) to lecithin (egg yolk phosphatidylcholine, EYL). The length of the micelles was quantitatively linked to the micellar composition by introducing a simple model. The model takes into account the partitioning of lecithin and bile salt between the bulk, cylindrical parts and the end caps of the micelles. The model also sheds light on the organization of the micelles, both in their cylindrical regions and end caps.}}, author = {{Madenci, Dilek and Salonen, Anniina and Schurtenberger, Peter and Pedersen, Jan Skov and Egelhaaf, Stefan U.}}, issn = {{1463-9084}}, language = {{eng}}, number = {{8}}, pages = {{3171--3178}}, publisher = {{Royal Society of Chemistry}}, series = {{Physical Chemistry Chemical Physics}}, title = {{Simple model for the growth behaviour of mixed lecithin-bile salt micelles}}, url = {{http://dx.doi.org/10.1039/c0cp01700k}}, doi = {{10.1039/c0cp01700k}}, volume = {{13}}, year = {{2011}}, }