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Alkohol og øvre gastrointestinal cancer Resultater fra Hovedstadens Center for Prospektive Befolkningsstudier

Grønbæk, Morten N. ; Becker, Povl Ulrik ; Johansen, Ditte ; Tønnesen, Hanne LU ; Jensen, Gorm and Sørensen, Thorkild I.A. (1999) In Ugeskrift for Laeger 161(45). p.6196-6199
Abstract

The present population based cohort study investigates the association between alcohol intake and cancer of the upper digestive tract. The design was prospective with baseline assessment of intake of beer, wine and spirits, smoking habits, educational level and 2-19 years' follow up on risk of upper digestive tract cancer (oropharyngeal and oesophageal). During a mean follow up of 13.5 years, 156 subjects developed upper digestive tract cancer. Compared with non-drinkers (drinkers of <1 drink/week), subjects who drank 7-21 beers or spirits a week but no wine were at a risk of 3.0 (95% confidence interval 1.5 to 6.1), whereas those who had the same total alcohol intake but with wine as ≥30% of their intake had a risk of 0.5 (0.2 to... (More)

The present population based cohort study investigates the association between alcohol intake and cancer of the upper digestive tract. The design was prospective with baseline assessment of intake of beer, wine and spirits, smoking habits, educational level and 2-19 years' follow up on risk of upper digestive tract cancer (oropharyngeal and oesophageal). During a mean follow up of 13.5 years, 156 subjects developed upper digestive tract cancer. Compared with non-drinkers (drinkers of <1 drink/week), subjects who drank 7-21 beers or spirits a week but no wine were at a risk of 3.0 (95% confidence interval 1.5 to 6.1), whereas those who had the same total alcohol intake but with wine as ≥30% of their intake had a risk of 0.5 (0.2 to 1.4). Drinkers of >21 beers and spirits but no wine had a relative risk of 5.2 (2.7 to 10.2) compared with non-drinkers, whereas those who drank the same amount, but included wine in their alcohol intake, had a relative risk of 1.7 (0.6 to 4.4). In conclusion, a moderate intake of wine probably does not increase the risk of upper digestive tract cancer, whereas a moderate intake of beer or spirits increases the risk considerably.

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author
; ; ; ; and
alternative title
Alcohol and upper digestive tract cancer. Results from prospective populations studies
publishing date
type
Contribution to journal
publication status
published
in
Ugeskrift for Laeger
volume
161
issue
45
pages
6196 - 6199
publisher
Den Almindelige Danske Lægeforening
external identifiers
  • scopus:0346303079
ISSN
0041-5782
language
Danish
LU publication?
no
id
3d50d01c-d4a2-4ee7-a823-708184d38289
date added to LUP
2022-10-27 16:56:18
date last changed
2023-01-04 06:40:30
@article{3d50d01c-d4a2-4ee7-a823-708184d38289,
  abstract     = {{<p>The present population based cohort study investigates the association between alcohol intake and cancer of the upper digestive tract. The design was prospective with baseline assessment of intake of beer, wine and spirits, smoking habits, educational level and 2-19 years' follow up on risk of upper digestive tract cancer (oropharyngeal and oesophageal). During a mean follow up of 13.5 years, 156 subjects developed upper digestive tract cancer. Compared with non-drinkers (drinkers of &lt;1 drink/week), subjects who drank 7-21 beers or spirits a week but no wine were at a risk of 3.0 (95% confidence interval 1.5 to 6.1), whereas those who had the same total alcohol intake but with wine as ≥30% of their intake had a risk of 0.5 (0.2 to 1.4). Drinkers of &gt;21 beers and spirits but no wine had a relative risk of 5.2 (2.7 to 10.2) compared with non-drinkers, whereas those who drank the same amount, but included wine in their alcohol intake, had a relative risk of 1.7 (0.6 to 4.4). In conclusion, a moderate intake of wine probably does not increase the risk of upper digestive tract cancer, whereas a moderate intake of beer or spirits increases the risk considerably.</p>}},
  author       = {{Grønbæk, Morten N. and Becker, Povl Ulrik and Johansen, Ditte and Tønnesen, Hanne and Jensen, Gorm and Sørensen, Thorkild I.A.}},
  issn         = {{0041-5782}},
  language     = {{dan}},
  number       = {{45}},
  pages        = {{6196--6199}},
  publisher    = {{Den Almindelige Danske Lægeforening}},
  series       = {{Ugeskrift for Laeger}},
  title        = {{Alkohol og øvre gastrointestinal cancer Resultater fra Hovedstadens Center for Prospektive Befolkningsstudier}},
  volume       = {{161}},
  year         = {{1999}},
}