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Search for the human papillomavirus in nasal polyps, using a polymerase chain reaction-method

Becker, M LU orcid ; Forslund, O ; Hansson, B G LU and Malm, L LU (1994) In Journal of Otolaryngology - Head and Neck Surgery 23(5). p.6-344
Abstract

Viral etiology of nasal polyps was postulated as many as 40 years ago, but so far, no study has shown an association or causal relation between any specific virus and nasal polyps. By using the polymerase chain reaction (PCR) technique, nasal polyps from both 10 patients with intolerance to nonsteroidal anti-inflammatory drugs (NSAID intolerance) (e.g., Aspirin) and from 10 patients with no history of NSAID intolerance were studied for the presence of papillomavirus DNA. Nasal mucosa from 10 patients who had undergone surgery for septoplasty served as controls. The PCR test used covers approximately 30 different types of human papillomaviruses. In this test, all tissue samples studied were found negative for papillomavirus DNA.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Aged, Anti-Inflammatory Agents, Non-Steroidal/adverse effects, Asthma/complications, DNA, Viral/analysis, Drug Hypersensitivity/complications, Female, Gene Amplification, Humans, Male, Middle Aged, Nasal Mucosa/virology, Nasal Polyps/virology, Nasal Septum/surgery, Papillomaviridae/genetics, Papillomavirus Infections/diagnosis, Polymerase Chain Reaction, Rhinoplasty, Tumor Virus Infections/diagnosis
in
Journal of Otolaryngology - Head and Neck Surgery
volume
23
issue
5
pages
3 pages
publisher
BioMed Central (BMC)
external identifiers
  • pmid:7807638
  • scopus:0027942918
ISSN
0381-6605
language
English
LU publication?
yes
id
3e8a47f4-a1fe-4f44-bad0-dffa418eea79
date added to LUP
2021-04-19 16:32:29
date last changed
2024-01-05 10:00:21
@article{3e8a47f4-a1fe-4f44-bad0-dffa418eea79,
  abstract     = {{<p>Viral etiology of nasal polyps was postulated as many as 40 years ago, but so far, no study has shown an association or causal relation between any specific virus and nasal polyps. By using the polymerase chain reaction (PCR) technique, nasal polyps from both 10 patients with intolerance to nonsteroidal anti-inflammatory drugs (NSAID intolerance) (e.g., Aspirin) and from 10 patients with no history of NSAID intolerance were studied for the presence of papillomavirus DNA. Nasal mucosa from 10 patients who had undergone surgery for septoplasty served as controls. The PCR test used covers approximately 30 different types of human papillomaviruses. In this test, all tissue samples studied were found negative for papillomavirus DNA.</p>}},
  author       = {{Becker, M and Forslund, O and Hansson, B G and Malm, L}},
  issn         = {{0381-6605}},
  keywords     = {{Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal/adverse effects; Asthma/complications; DNA, Viral/analysis; Drug Hypersensitivity/complications; Female; Gene Amplification; Humans; Male; Middle Aged; Nasal Mucosa/virology; Nasal Polyps/virology; Nasal Septum/surgery; Papillomaviridae/genetics; Papillomavirus Infections/diagnosis; Polymerase Chain Reaction; Rhinoplasty; Tumor Virus Infections/diagnosis}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{6--344}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{Journal of Otolaryngology - Head and Neck Surgery}},
  title        = {{Search for the human papillomavirus in nasal polyps, using a polymerase chain reaction-method}},
  volume       = {{23}},
  year         = {{1994}},
}