Diagnoses of schizophrenia, schizotypal and delusional disorders among people with intellectual disabilities compared to the general population: A register study in Skåne, in southern Sweden
Sandberg, Magnus LU
; Kristensson, Jimmie
LU
and Axmon, Anna
LU
(2023)
14th Congress of the European Association for Mental Health in Intellectual Disability
- Abstract
- Background: People with intellectual disabilities (ID) may be at higher risk of psychiatric disorders than the general population. However, few studies investigate the role of demographic factors.
Methods: This register-based study includes all people living in Skåne, Sweden, on January 1st, 2014. The ID cohort comprises those who received support and service for people with functional impairments and those with diagnosis of ID or Down Syndrome (n=14715). The remaining population of Skåne formed the general population cohort (GenPop; n=1258644). Data on diagnoses of schizophrenia, schizotypal and delusional disorders were collected for 2014-2021. All analyses considered sex, age group and own and parent origin as potential... (More) - Background: People with intellectual disabilities (ID) may be at higher risk of psychiatric disorders than the general population. However, few studies investigate the role of demographic factors.
Methods: This register-based study includes all people living in Skåne, Sweden, on January 1st, 2014. The ID cohort comprises those who received support and service for people with functional impairments and those with diagnosis of ID or Down Syndrome (n=14715). The remaining population of Skåne formed the general population cohort (GenPop; n=1258644). Data on diagnoses of schizophrenia, schizotypal and delusional disorders were collected for 2014-2021. All analyses considered sex, age group and own and parent origin as potential confounders and effect modifiers.
Results/Aims:The aim of this study is to compare diagnoses of schizophrenia, schizotypal and delusional disorders among people with ID compared to the general population accounting for demographic factors. People with ID had higher risk of all investigated diagnoses. The prevalence of schizophrenia was 3.1% and unspecified nonorganic psychosis 2.8% in the ID cohort compared to 0.3% and 0.2% in GenPop cohort (RR 9.2, 95% CI 8.7-10.5 and RR 12.8 95% CI 11.5-14.2 respectively). The risk increases remained after adjusting for demographic factors (RR 13.6 95% CI 12.3 15.0 and RR 16.0 95% CI 14.4-17.9). Stratified analyses revealed that the risk of schizophrenia associated with ID was higher among women, whereas that of unspecified nonorganic psychosis was higher among men. Adults with ID were more at risk than children/adolescents and older people of being diagnosed unspecified nonorganic psychosis, while older people were more likely to be diagnosed with schizophrenia.
Conclusions: Even when considering demographic factors, people with ID are in general more at risk of diagnoses of schizophrenia, schizotypal and delusional disorders compared to the general population, in particular schizophrenia and unspecified nonorganic psychosis. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3f08aa1d-f759-456a-b3f6-5b86d0fe2472
- author
- Sandberg, Magnus
LU
; Kristensson, Jimmie
LU
and Axmon, Anna
LU
- organization
- publishing date
- 2023
- type
- Contribution to conference
- publication status
- published
- subject
- conference name
- 14th Congress of the European Association for Mental Health in Intellectual Disability
- conference location
- Helsinki, Finland
- conference dates
- 2023-09-21 - 2023-09-23
- project
- Health care utilization in primary and specialist care among people with intellectual disability: A longitudinal register study
- Support, health care, end-of-life care, and causes of death among people with intellectual disability: Effects of the Covid-19 pandemic
- language
- English
- LU publication?
- yes
- id
- 3f08aa1d-f759-456a-b3f6-5b86d0fe2472
- date added to LUP
- 2024-03-27 10:31:37
- date last changed
- 2026-03-12 11:12:00
@misc{3f08aa1d-f759-456a-b3f6-5b86d0fe2472,
abstract = {{Background: People with intellectual disabilities (ID) may be at higher risk of psychiatric disorders than the general population. However, few studies investigate the role of demographic factors.<br/><br/>Methods: This register-based study includes all people living in Skåne, Sweden, on January 1st, 2014. The ID cohort comprises those who received support and service for people with functional impairments and those with diagnosis of ID or Down Syndrome (n=14715). The remaining population of Skåne formed the general population cohort (GenPop; n=1258644). Data on diagnoses of schizophrenia, schizotypal and delusional disorders were collected for 2014-2021. All analyses considered sex, age group and own and parent origin as potential confounders and effect modifiers.<br/><br/>Results/Aims:The aim of this study is to compare diagnoses of schizophrenia, schizotypal and delusional disorders among people with ID compared to the general population accounting for demographic factors. People with ID had higher risk of all investigated diagnoses. The prevalence of schizophrenia was 3.1% and unspecified nonorganic psychosis 2.8% in the ID cohort compared to 0.3% and 0.2% in GenPop cohort (RR 9.2, 95% CI 8.7-10.5 and RR 12.8 95% CI 11.5-14.2 respectively). The risk increases remained after adjusting for demographic factors (RR 13.6 95% CI 12.3 15.0 and RR 16.0 95% CI 14.4-17.9). Stratified analyses revealed that the risk of schizophrenia associated with ID was higher among women, whereas that of unspecified nonorganic psychosis was higher among men. Adults with ID were more at risk than children/adolescents and older people of being diagnosed unspecified nonorganic psychosis, while older people were more likely to be diagnosed with schizophrenia.<br/><br/>Conclusions: Even when considering demographic factors, people with ID are in general more at risk of diagnoses of schizophrenia, schizotypal and delusional disorders compared to the general population, in particular schizophrenia and unspecified nonorganic psychosis.}},
author = {{Sandberg, Magnus and Kristensson, Jimmie and Axmon, Anna}},
language = {{eng}},
title = {{Diagnoses of schizophrenia, schizotypal and delusional disorders among people with intellectual disabilities compared to the general population: A register study in Skåne, in southern Sweden}},
year = {{2023}},
}