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Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician : Case Reports of V/P SPECT

Bajc, Marika LU ; Hedeer, Fredrik LU ; Lindqvist, Ari and Trägårdh, Elin LU (2021) In Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine 15.
Abstract

V/P SPECT from 4 consecutive patients with COVID-19 suggests that ventilation and perfusion images may be applied to diagnose or exclude pulmonary embolism, verify nonsegmental diversion of perfusion from the ventilated areas (dead space ventilation) that may represent inflammation of the pulmonary vasculature, detect the reversed mismatch of poor ventilation and better preserved perfusion (shunt perfusion) in bilateral pulmonary inflammation and indicate redistribution of lung perfusion (antigravitational hyperperfusion) due to cardiac congestion. V/P mismatch and reversed mismatch may be extensive enough to diminish dramatically preserved matching ventilation/perfusion and to induce severe hypoxemia in COVID-19.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
COVID-19, perfusion, pulmonary embolism, SARS-CoV-2, SPECT, Ventilation
in
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine
volume
15
publisher
Libertas Academica
external identifiers
  • scopus:85111007527
  • pmid:34349582
ISSN
1179-5484
DOI
10.1177/11795484211030159
language
English
LU publication?
yes
id
3f6482e1-2091-4e8a-8607-e6417949c2c6
date added to LUP
2022-03-07 17:03:53
date last changed
2024-06-07 15:37:23
@article{3f6482e1-2091-4e8a-8607-e6417949c2c6,
  abstract     = {{<p>V/P SPECT from 4 consecutive patients with COVID-19 suggests that ventilation and perfusion images may be applied to diagnose or exclude pulmonary embolism, verify nonsegmental diversion of perfusion from the ventilated areas (dead space ventilation) that may represent inflammation of the pulmonary vasculature, detect the reversed mismatch of poor ventilation and better preserved perfusion (shunt perfusion) in bilateral pulmonary inflammation and indicate redistribution of lung perfusion (antigravitational hyperperfusion) due to cardiac congestion. V/P mismatch and reversed mismatch may be extensive enough to diminish dramatically preserved matching ventilation/perfusion and to induce severe hypoxemia in COVID-19.</p>}},
  author       = {{Bajc, Marika and Hedeer, Fredrik and Lindqvist, Ari and Trägårdh, Elin}},
  issn         = {{1179-5484}},
  keywords     = {{COVID-19; perfusion; pulmonary embolism; SARS-CoV-2; SPECT; Ventilation}},
  language     = {{eng}},
  publisher    = {{Libertas Academica}},
  series       = {{Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine}},
  title        = {{Assessment of Ventilation and Perfusion in Patients with COVID-19 Discloses Unique Information of Pulmonary Function to a Clinician : Case Reports of V/P SPECT}},
  url          = {{http://dx.doi.org/10.1177/11795484211030159}},
  doi          = {{10.1177/11795484211030159}},
  volume       = {{15}},
  year         = {{2021}},
}