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Mesoporous Silica SBA-15 - Formation, Modification and Application

Kjellman, Tomas LU (2013)
Abstract (Swedish)
Popular Abstract in Swedish

I början 1990-talet upptäcktes att det var möjligt att syntetisera så kallad mesoporös silika. Upptäckten fick stor uppmärksamhet då materialen har ett flertal intressanta egenskaper som inkluderar ett stort antal porer med väldefinierad diameter, jämn partikelstorlek och möjligheten att påverka dessa och andra egenskaper.

I den här avhandlingen har det mesoporösa silikamaterialet SBA-15 studerats i tre olika delprojekt. I det första projektet studeras vad som styr bildandet av partiklar av SBA-15, och vad som kontrollerar deras storlek. I det andra projektet studeras hur materialets porer kan påverkas för att få ett material med specifikt anpassade egenskaper. Slutligen har SBA-15... (More)
Popular Abstract in Swedish

I början 1990-talet upptäcktes att det var möjligt att syntetisera så kallad mesoporös silika. Upptäckten fick stor uppmärksamhet då materialen har ett flertal intressanta egenskaper som inkluderar ett stort antal porer med väldefinierad diameter, jämn partikelstorlek och möjligheten att påverka dessa och andra egenskaper.

I den här avhandlingen har det mesoporösa silikamaterialet SBA-15 studerats i tre olika delprojekt. I det första projektet studeras vad som styr bildandet av partiklar av SBA-15, och vad som kontrollerar deras storlek. I det andra projektet studeras hur materialets porer kan påverkas för att få ett material med specifikt anpassade egenskaper. Slutligen har SBA-15 partiklar använts för att studera två mer praktiska problem. Det första handlar om att försöka deponera partiklarna på en yta så att dess porer hamnar vinkelrät mot ytan, vilket it sig skulle ge en yta med intressanta egenskaper. Det andra handlar om att försöka använda SBA-15 som en bärare av cancerläkemedlet Dasatinib, och sedan studera hur läkemedlet lämnar SBA-15 material som har olika porer.

Genom arbetet finns en sammanhängande röd tråd som visar hur en god förståelse för de fundamentala processer som styr materialets bildande kan användas för att influera materialets egenskaper, vilket i sin tur kan utnyttjas för att försöka lösa praktiska problem. (Less)
Abstract
Several aspects related to the mesoporous silica material SBA-15 have been studied through the use of a wide range of experimental techniques, including low voltage high-resolution scanning electron microscopy, small angle X-ray scattering and nitrogen sorption. This work contains three parts, which are in many ways overlapping. The first part deals with the formation of SBA-15, it is found that a mechanism of transient colloidal stability governs the growth of particles. In the second part, a modified experimental protocol is developed in order to independently fine-tune the intrawall porosity and primary mesoporosity of SBA-

15. Furthermore, the influence of solvent conditions on the development of structural details such as... (More)
Several aspects related to the mesoporous silica material SBA-15 have been studied through the use of a wide range of experimental techniques, including low voltage high-resolution scanning electron microscopy, small angle X-ray scattering and nitrogen sorption. This work contains three parts, which are in many ways overlapping. The first part deals with the formation of SBA-15, it is found that a mechanism of transient colloidal stability governs the growth of particles. In the second part, a modified experimental protocol is developed in order to independently fine-tune the intrawall porosity and primary mesoporosity of SBA-

15. Furthermore, the influence of solvent conditions on the development of structural details such as plugs and pore corrugations is investigated. Finally the last part deals with the use of SBA-15 material in applied problems, including controlled particle deposition and drug delivery. No matter the topic, the aim is to always base the applied strategies on a solid foundation of the understanding of the

basic physiochemical processes relevant to the system under study. The work is presented in a way that there is a red line going through, showing how good understanding of fundamental processes opens up for possibilities to tune material properties, which in turn improves the material for use in application. (Less)
Please use this url to cite or link to this publication:
author
opponent
  • Lennart, Bergström, Department of Materials and Environmental Chemistry, Stockholm University
organization
publishing date
type
Thesis
publication status
published
subject
keywords
SBA-15, Mesoporous Silica, Intrawall pores, Colloidal Stability, Drug release, Deposition
pages
170 pages
publisher
Department of Chemistry, Lund University
defense location
Lecture Hall B, Center for Chemistry and Chemical Engineering
defense date
2013-10-04 10:30
ISBN
978-91-7422-331-6
language
English
LU publication?
yes
id
545a58e7-b9f9-49ba-8f34-57ceb7d320f0 (old id 4004240)
date added to LUP
2013-09-02 12:04:17
date last changed
2016-09-19 08:45:08
@phdthesis{545a58e7-b9f9-49ba-8f34-57ceb7d320f0,
  abstract     = {Several aspects related to the mesoporous silica material SBA-15 have been studied through the use of a wide range of experimental techniques, including low voltage high-resolution scanning electron microscopy, small angle X-ray scattering and nitrogen sorption. This work contains three parts, which are in many ways overlapping. The first part deals with the formation of SBA-15, it is found that a mechanism of transient colloidal stability governs the growth of particles. In the second part, a modified experimental protocol is developed in order to independently fine-tune the intrawall porosity and primary mesoporosity of SBA-<br/><br>
15. Furthermore, the influence of solvent conditions on the development of structural details such as plugs and pore corrugations is investigated. Finally the last part deals with the use of SBA-15 material in applied problems, including controlled particle deposition and drug delivery. No matter the topic, the aim is to always base the applied strategies on a solid foundation of the understanding of the<br/><br>
basic physiochemical processes relevant to the system under study. The work is presented in a way that there is a red line going through, showing how good understanding of fundamental processes opens up for possibilities to tune material properties, which in turn improves the material for use in application.},
  author       = {Kjellman, Tomas},
  isbn         = {978-91-7422-331-6},
  keyword      = {SBA-15,Mesoporous Silica,Intrawall pores,Colloidal Stability,Drug release,Deposition},
  language     = {eng},
  pages        = {170},
  publisher    = {Department of Chemistry, Lund University},
  school       = {Lund University},
  title        = {Mesoporous Silica SBA-15 - Formation, Modification and Application},
  year         = {2013},
}