Why does dosage compensation differ between XY and ZW taxa?
Naurin, Sara LU ; Hansson, Bengt LU
; Bensch, Staffan
LU
and Hasselquist, Dennis
LU
(2010)
In Trends in Genetics
26(1).
p.15-20
- Abstract
- Recent studies have demonstrated an extensive male bias in the gene expression on Z chromosomes in species with a ZW sex determination (e.g. birds), suggesting that ZW females have incomplete dosage compensation. We propose that the extensive male bias on Z chromosomes is caused by the functional properties of male-adapted genes, which make them unsuitable for high expression in females, and that ZW females are dosage-compensated to a point where they have achieved enough compensation to maintain the integrity of critical networks. In ZW systems, Z chromosomes spend two-thirds of their evolutionary time in males, and pronounced sexual selection in males and the male mutation bias can interact and affect levels of sexual antagonism, causing... (More)
- Recent studies have demonstrated an extensive male bias in the gene expression on Z chromosomes in species with a ZW sex determination (e.g. birds), suggesting that ZW females have incomplete dosage compensation. We propose that the extensive male bias on Z chromosomes is caused by the functional properties of male-adapted genes, which make them unsuitable for high expression in females, and that ZW females are dosage-compensated to a point where they have achieved enough compensation to maintain the integrity of critical networks. In ZW systems, Z chromosomes spend two-thirds of their evolutionary time in males, and pronounced sexual selection in males and the male mutation bias can interact and affect levels of sexual antagonism, causing more extensive male bias in gene expression on Z-linked genes. These patterns and processes contrast with those acting on genes on the X chromosome in XY species, and might help explain the discrepancies in the degree of sex-biased gene expression and dosage compensation in XY and ZW systems. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1523938
- author
- Naurin, Sara
LU
; Hansson, Bengt
LU
; Bensch, Staffan
LU
and Hasselquist, Dennis
LU
- organization
- publishing date
- 2010
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Trends in Genetics
- volume
- 26
- issue
- 1
- pages
- 15 - 20
- publisher
- Elsevier
- external identifiers
-
- wos:000273884400004
- scopus:72449137274
- pmid:19963300
- ISSN
- 1362-4555
- DOI
- 10.1016/j.tig.2009.11.006
- language
- English
- LU publication?
- yes
- id
- 40893920-7309-48e7-bec7-8cb229b3a019 (old id 1523938)
- date added to LUP
- 2016-04-04 12:11:07
- date last changed
- 2024-04-27 21:31:23
@article{40893920-7309-48e7-bec7-8cb229b3a019,
abstract = {{Recent studies have demonstrated an extensive male bias in the gene expression on Z chromosomes in species with a ZW sex determination (e.g. birds), suggesting that ZW females have incomplete dosage compensation. We propose that the extensive male bias on Z chromosomes is caused by the functional properties of male-adapted genes, which make them unsuitable for high expression in females, and that ZW females are dosage-compensated to a point where they have achieved enough compensation to maintain the integrity of critical networks. In ZW systems, Z chromosomes spend two-thirds of their evolutionary time in males, and pronounced sexual selection in males and the male mutation bias can interact and affect levels of sexual antagonism, causing more extensive male bias in gene expression on Z-linked genes. These patterns and processes contrast with those acting on genes on the X chromosome in XY species, and might help explain the discrepancies in the degree of sex-biased gene expression and dosage compensation in XY and ZW systems.}},
author = {{Naurin, Sara and Hansson, Bengt and Bensch, Staffan and Hasselquist, Dennis}},
issn = {{1362-4555}},
language = {{eng}},
number = {{1}},
pages = {{15--20}},
publisher = {{Elsevier}},
series = {{Trends in Genetics}},
title = {{Why does dosage compensation differ between XY and ZW taxa?}},
url = {{http://dx.doi.org/10.1016/j.tig.2009.11.006}},
doi = {{10.1016/j.tig.2009.11.006}},
volume = {{26}},
year = {{2010}},
}