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Post resuscitation care - What are the therapeutic alternatives and what do we know?

Herlitz, J ; Castren, M ; Friberg, Hans LU ; Nolan, J ; Skrifvars, M ; Sunde, K and Steene, PA (2006) In Resuscitation 69(1). p.15-22
Abstract
A large proportion of deaths in the Western World are caused by ischaemic heart disease. Among these patients a majority die outside hospital due to sudden cardiac death. The prognosis among these patients is in general, poor. However, a significant proportion are admitted to a hospital ward alive. The proportion of patients who survive the hospital phase of an out of hospital cardiac arrest varies considerably. Several treatment strategies are applicable during the post resuscitation care phase, but the level of evidence is weak for most of them. Four treatments are recommended for selected patients based on relatively good clinical evidence: therapeutic hypothermia, beta-blockers, coronary artery bypass grafting, and an implantable... (More)
A large proportion of deaths in the Western World are caused by ischaemic heart disease. Among these patients a majority die outside hospital due to sudden cardiac death. The prognosis among these patients is in general, poor. However, a significant proportion are admitted to a hospital ward alive. The proportion of patients who survive the hospital phase of an out of hospital cardiac arrest varies considerably. Several treatment strategies are applicable during the post resuscitation care phase, but the level of evidence is weak for most of them. Four treatments are recommended for selected patients based on relatively good clinical evidence: therapeutic hypothermia, beta-blockers, coronary artery bypass grafting, and an implantable cardioverter defibrillator. The patient's cerebral function might influence implementation of the latter two alternatives. There is some evidence for revascutarisation treatment in patients with suspected myocardial infarction. On pathophysiological grounds, an early coronary angiogram is a reasonable alternative. Further randomised clinical trials of other post resuscitation therapies are essential. (c) 2005 Elsevier Ireland Ltd. All rights reserved. (Less)
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cardiac arrest, treatment, post resuscitation
in
Resuscitation
volume
69
issue
1
pages
15 - 22
publisher
Elsevier
external identifiers
  • wos:000237208700003
  • scopus:33645879246
ISSN
1873-1570
DOI
10.1016/j.resuscitation.2005.08.006
language
English
LU publication?
yes
id
2df8b317-04d2-441f-9624-694d9e103400 (old id 410240)
date added to LUP
2016-04-01 12:06:00
date last changed
2020-05-06 02:32:35
@article{2df8b317-04d2-441f-9624-694d9e103400,
  abstract     = {A large proportion of deaths in the Western World are caused by ischaemic heart disease. Among these patients a majority die outside hospital due to sudden cardiac death. The prognosis among these patients is in general, poor. However, a significant proportion are admitted to a hospital ward alive. The proportion of patients who survive the hospital phase of an out of hospital cardiac arrest varies considerably. Several treatment strategies are applicable during the post resuscitation care phase, but the level of evidence is weak for most of them. Four treatments are recommended for selected patients based on relatively good clinical evidence: therapeutic hypothermia, beta-blockers, coronary artery bypass grafting, and an implantable cardioverter defibrillator. The patient's cerebral function might influence implementation of the latter two alternatives. There is some evidence for revascutarisation treatment in patients with suspected myocardial infarction. On pathophysiological grounds, an early coronary angiogram is a reasonable alternative. Further randomised clinical trials of other post resuscitation therapies are essential. (c) 2005 Elsevier Ireland Ltd. All rights reserved.},
  author       = {Herlitz, J and Castren, M and Friberg, Hans and Nolan, J and Skrifvars, M and Sunde, K and Steene, PA},
  issn         = {1873-1570},
  language     = {eng},
  number       = {1},
  pages        = {15--22},
  publisher    = {Elsevier},
  series       = {Resuscitation},
  title        = {Post resuscitation care - What are the therapeutic alternatives and what do we know?},
  url          = {http://dx.doi.org/10.1016/j.resuscitation.2005.08.006},
  doi          = {10.1016/j.resuscitation.2005.08.006},
  volume       = {69},
  year         = {2006},
}