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Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity

Shi, W ; Liu, Y ; Liu, B ; Song, YG ; Xu, YK ; Wang, HM ; Sha, YL ; Xu, GZ ; Styring, Stenbjörn LU and Huang, P (2006) In Journal of Coordination Chemistry 59(2). p.119-130
Abstract
The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT)... (More)
The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT) transitions in the UV region and d-d transitions in the visible region. Solvent molecules coordinated to the Mn(III) ion in the crystal are thought to retain their coordination in solution. It is shown that 1 has reaction activity with the superoxide ion, as indicated by inhibition of pyrogallol autoxidation and by spin trapping electron paramagnetic resonance (EPR) spectroscopy. The N3O3 ligand set in 1 is similar to that in native MnSOD (superoxide dismutatase) in the substrate-bound state. The correlation between the ligand set in 1 and its reaction with the superoxide ion is discussed. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
2-dimethyl-3, 4-dihydro-2H-pyrrole-1-oxide, spin trap, pyrogallol, autoxidation, 2, superoxide ion reactivity, superoxide dismutase, structure, X-ray, pyridine, Manganese(III), 2-o-hydroxyphenylbenzimidazole
in
Journal of Coordination Chemistry
volume
59
issue
2
pages
119 - 130
publisher
Taylor & Francis
external identifiers
  • wos:000235500600001
  • scopus:29044438159
ISSN
1026-7441
DOI
10.1080/00958970500249814
language
English
LU publication?
yes
id
8a9edf47-7a6b-437f-b863-14c0db2d870c (old id 417110)
date added to LUP
2016-04-01 12:29:36
date last changed
2021-02-17 02:13:52
@article{8a9edf47-7a6b-437f-b863-14c0db2d870c,
  abstract     = {The complex [Mn-III(HL)(L)(py)(CH3OH)](CH3OH)-C-. (H2L=2-ortho-hydroxyphenylbenzimidazole, py pyridine), 1, has been characterized spectroscopically and by X-ray crystallography. The complex is triclinic, space group P-1(-) with a = 10.396(2), b = 10.7340(10), c = 15.193(2) angstrom, alpha = 73.193(4)degrees, beta = 76.283(8)degrees, gamma = 61.400(40)degrees, V = 1415.1(4)angstrom(3), Z = 2, D-c = 1.445 Mg m(-3), M-r = 615.56, mu = 0.515 mm(-1), F(000) = 640, R = 0.0631, wR = 0.1525. Manganese is six-coordinate in an N3O3 ligand sphere created by two bidentate H2L ligands and solvent molecules with a slightly distorted, axially elongated octahedral geometry. Electronic absorption spectra show pi-pi* and Ligand Metal Charge Transfer (LMCT) transitions in the UV region and d-d transitions in the visible region. Solvent molecules coordinated to the Mn(III) ion in the crystal are thought to retain their coordination in solution. It is shown that 1 has reaction activity with the superoxide ion, as indicated by inhibition of pyrogallol autoxidation and by spin trapping electron paramagnetic resonance (EPR) spectroscopy. The N3O3 ligand set in 1 is similar to that in native MnSOD (superoxide dismutatase) in the substrate-bound state. The correlation between the ligand set in 1 and its reaction with the superoxide ion is discussed.},
  author       = {Shi, W and Liu, Y and Liu, B and Song, YG and Xu, YK and Wang, HM and Sha, YL and Xu, GZ and Styring, Stenbjörn and Huang, P},
  issn         = {1026-7441},
  language     = {eng},
  number       = {2},
  pages        = {119--130},
  publisher    = {Taylor & Francis},
  series       = {Journal of Coordination Chemistry},
  title        = {Synthesis and characterization of a six-coordinate monomeric Mn(III) complex with SOD-like activity},
  url          = {http://dx.doi.org/10.1080/00958970500249814},
  doi          = {10.1080/00958970500249814},
  volume       = {59},
  year         = {2006},
}