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Usage Tests of Oak Moss Absolutes Containing High and Low Levels of Atranol and Chloroatranol.

Mowitz, Martin LU ; Svedman, Cecilia LU ; Zimerson, Erik LU and Bruze, Magnus LU (2014) In Acta Dermato-Venereologica 94(4). p.398-402
Abstract
Atranol and chloroatranol are strong contact allergens in oak moss absolute, a lichen extract used in perfumery. Fifteen subjects with contact allergy to oak moss absolute underwent a repeated open application test (ROAT) using solutions of an untreated oak moss absolute (sample A) and an oak moss absolute with reduced content of atranol and chloroatranol (sample B). All subjects were in addition patch-tested with serial dilutions of samples A and B. Statistically significantly more subjects reacted to sample A than to sample B in the patch tests. No corresponding difference was observed in the ROAT, though there was a significant difference in the time required to elicit a positive reaction. Still, the ROAT indicates that the use of a... (More)
Atranol and chloroatranol are strong contact allergens in oak moss absolute, a lichen extract used in perfumery. Fifteen subjects with contact allergy to oak moss absolute underwent a repeated open application test (ROAT) using solutions of an untreated oak moss absolute (sample A) and an oak moss absolute with reduced content of atranol and chloroatranol (sample B). All subjects were in addition patch-tested with serial dilutions of samples A and B. Statistically significantly more subjects reacted to sample A than to sample B in the patch tests. No corresponding difference was observed in the ROAT, though there was a significant difference in the time required to elicit a positive reaction. Still, the ROAT indicates that the use of a cosmetic product containing oak moss absolute with reduced levels of atranol and chloroatranol is capable of eliciting an allergic reaction in previously sensitised individuals. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
94
issue
4
pages
398 - 402
publisher
Medical Journals Limited
external identifiers
  • pmid:24287679
  • wos:000339416100005
  • scopus:84902783812
ISSN
1651-2057
DOI
10.2340/00015555-1725
language
English
LU publication?
yes
id
0fdc5bda-c645-4a69-a734-4cadc0baf502 (old id 4178798)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24287679?dopt=Abstract
date added to LUP
2013-12-02 17:54:20
date last changed
2017-11-05 03:23:54
@article{0fdc5bda-c645-4a69-a734-4cadc0baf502,
  abstract     = {Atranol and chloroatranol are strong contact allergens in oak moss absolute, a lichen extract used in perfumery. Fifteen subjects with contact allergy to oak moss absolute underwent a repeated open application test (ROAT) using solutions of an untreated oak moss absolute (sample A) and an oak moss absolute with reduced content of atranol and chloroatranol (sample B). All subjects were in addition patch-tested with serial dilutions of samples A and B. Statistically significantly more subjects reacted to sample A than to sample B in the patch tests. No corresponding difference was observed in the ROAT, though there was a significant difference in the time required to elicit a positive reaction. Still, the ROAT indicates that the use of a cosmetic product containing oak moss absolute with reduced levels of atranol and chloroatranol is capable of eliciting an allergic reaction in previously sensitised individuals.},
  author       = {Mowitz, Martin and Svedman, Cecilia and Zimerson, Erik and Bruze, Magnus},
  issn         = {1651-2057},
  language     = {eng},
  number       = {4},
  pages        = {398--402},
  publisher    = {Medical Journals Limited},
  series       = {Acta Dermato-Venereologica},
  title        = {Usage Tests of Oak Moss Absolutes Containing High and Low Levels of Atranol and Chloroatranol.},
  url          = {http://dx.doi.org/10.2340/00015555-1725},
  volume       = {94},
  year         = {2014},
}