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Automatic Measurements of Diameter, Distension and Intima Media Thickness of the Aorta in Premature Rabbit Pups Using B-Mode Images.

Erlöv, Tobias LU ; Segstedt, Simon LU ; Milton, Patrik LU ; Sveinsdottir, Snjolaug LU ; Jansson, Tomas LU ; Persson, Hans W LU ; Ley, David LU and Cinthio, Magnus LU orcid (2014) In Ultrasound in Medicine and Biology 40(2). p.371-377
Abstract
To improve cardiovascular research, there is a growing need for arterial characterization in small animals. We developed a method, ARTIC (arterial characterization) for measuring lumen diameter, distension and intima media thickness (IMT). In this study ARTIC was used to automatically characterize the aorta of premature rabbit pups. Automatic measurements were compared with manual measurements, both performed by three observers. Diameter was 769 ± 140 μm (manual) and 766 ± 142 μm (automatic), distension was 35 ± 15 μm (manual) and 40 ± 12 μm (automatic) and IMT was 84 ± 11 μm (manual) and 88 ± 8 μm (automatic) (mean ± standard deviation). The variation in the measured diameter, distension and IMT ranged from 1.1% to 26.0% (manual) and from... (More)
To improve cardiovascular research, there is a growing need for arterial characterization in small animals. We developed a method, ARTIC (arterial characterization) for measuring lumen diameter, distension and intima media thickness (IMT). In this study ARTIC was used to automatically characterize the aorta of premature rabbit pups. Automatic measurements were compared with manual measurements, both performed by three observers. Diameter was 769 ± 140 μm (manual) and 766 ± 142 μm (automatic), distension was 35 ± 15 μm (manual) and 40 ± 12 μm (automatic) and IMT was 84 ± 11 μm (manual) and 88 ± 8 μm (automatic) (mean ± standard deviation). The variation in the measured diameter, distension and IMT ranged from 1.1% to 26.0% (manual) and from 1.0% to 9.0% (automatic). The intra-class correlation coefficient ranged from 33.0% to 99.3% (manual) and from 76.9% to 99.6% (automatic). The evaluation revealed that it is feasible to use ARTIC on B-mode images of arteries with small dimensions, which makes it a useful tool for arterial characterization in small animals. (Less)
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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Ultrasound in Medicine and Biology
volume
40
issue
2
pages
371 - 377
publisher
Elsevier
external identifiers
  • wos:000329221600012
  • pmid:24268455
  • scopus:84891635315
  • pmid:24268455
ISSN
0301-5629
DOI
10.1016/j.ultrasmedbio.2013.09.017
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Paediatrics (Lund) (013002000), Department of Electrical Measurements (011022000)
id
19347574-f12f-428c-8b39-5bb7978d2d09 (old id 4178994)
date added to LUP
2016-04-01 10:17:43
date last changed
2024-10-07 01:26:43
@article{19347574-f12f-428c-8b39-5bb7978d2d09,
  abstract     = {{To improve cardiovascular research, there is a growing need for arterial characterization in small animals. We developed a method, ARTIC (arterial characterization) for measuring lumen diameter, distension and intima media thickness (IMT). In this study ARTIC was used to automatically characterize the aorta of premature rabbit pups. Automatic measurements were compared with manual measurements, both performed by three observers. Diameter was 769 ± 140 μm (manual) and 766 ± 142 μm (automatic), distension was 35 ± 15 μm (manual) and 40 ± 12 μm (automatic) and IMT was 84 ± 11 μm (manual) and 88 ± 8 μm (automatic) (mean ± standard deviation). The variation in the measured diameter, distension and IMT ranged from 1.1% to 26.0% (manual) and from 1.0% to 9.0% (automatic). The intra-class correlation coefficient ranged from 33.0% to 99.3% (manual) and from 76.9% to 99.6% (automatic). The evaluation revealed that it is feasible to use ARTIC on B-mode images of arteries with small dimensions, which makes it a useful tool for arterial characterization in small animals.}},
  author       = {{Erlöv, Tobias and Segstedt, Simon and Milton, Patrik and Sveinsdottir, Snjolaug and Jansson, Tomas and Persson, Hans W and Ley, David and Cinthio, Magnus}},
  issn         = {{0301-5629}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{371--377}},
  publisher    = {{Elsevier}},
  series       = {{Ultrasound in Medicine and Biology}},
  title        = {{Automatic Measurements of Diameter, Distension and Intima Media Thickness of the Aorta in Premature Rabbit Pups Using B-Mode Images.}},
  url          = {{http://dx.doi.org/10.1016/j.ultrasmedbio.2013.09.017}},
  doi          = {{10.1016/j.ultrasmedbio.2013.09.017}},
  volume       = {{40}},
  year         = {{2014}},
}